As'adi Nayereh, Kariman Nourossadat, Mojab Faraz, Pourhoseingholi Mohammad Amin
M.Sc. of Midwifery, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ph.D. of Reproductive Health, Assistant Professor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Electron Physician. 2017 Aug 25;9(8):4952-4960. doi: 10.19082/4952. eCollection 2017 Aug.
Nipple fissure is a common problem in breastfeeding women, and the main reason for the early discontinuation of breastfeeding.
To determine the effect of Saqez (Pistacia atlantica) ointment on the treatment of nipple fissure and nipple pain in breastfeeding women.
This randomized clinical trial was conducted on 100 subjects admitted to the health centers in Tehran, Iran from mid-July to mid-November 2015. The subjects were randomly divided into two equal groups of 50 for the Saqez ointment group and the control group. The subjects were divided into the two groups through random allocation in Excel. The subjects were monitored on day 1, 3 and 7. Data were analyzed in SAS using the Cumulative Logit model and in SPSS-21 using Mann-Whitney, independent-samples t-test, the Chi square and Fisher's exact test.
No significant differences were observed between the two groups in terms of their demographic and fertility characteristics. The Cumulative Logit model showed that high levels of nipple fissure and pain were significantly less frequent in the Saqez group compared to the control group (p<0.001). There was about 83% reduction in the severity of fissure and 85 %in the severity of pain in the Saqez group compared to the control group (p<0.001).
Saqez ointment is more effective in the treatment of nipple fissures and pain than breast milk. As this study was done for the first time, judgment about the conclusive efficacy of Saqez ointment on the nipple fissure, needs further similar studies.
The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the Irct ID: IRCT2015080723535N1.
The authors received no financial support for the research, authorship, and/or publication of this article.
乳头皲裂是哺乳期女性的常见问题，也是早期停止母乳喂养的主要原因。
确定萨盖兹（大西洋黄连木）软膏对治疗哺乳期女性乳头皲裂和乳头疼痛的效果。
这项随机临床试验于2015年7月中旬至11月中旬在伊朗德黑兰的健康中心对100名受试者进行。受试者被随机分为两组，每组50人，分别为萨盖兹软膏组和对照组。通过Excel中的随机分配将受试者分为两组。在第1天、第3天和第7天对受试者进行监测。使用累积Logit模型在SAS中以及使用曼-惠特尼检验、独立样本t检验、卡方检验和费舍尔精确检验在SPSS-21中对数据进行分析。
两组在人口统计学和生育特征方面未观察到显著差异。累积Logit模型显示，与对照组相比，萨盖兹组乳头皲裂和疼痛程度较高的情况明显较少（p<0.001）。与对照组相比，萨盖兹组皲裂严重程度降低了约83%，疼痛严重程度降低了85%（p<0.001）。
萨盖兹软膏在治疗乳头皲裂和疼痛方面比母乳更有效。由于这项研究是首次进行，关于萨盖兹软膏对乳头皲裂的确切疗效的判断，需要进一步进行类似研究。
该试验在伊朗临床试验注册中心（http://www.irct.ir）注册，注册号为：IRCT2015080723535N1。
作者未获得该研究、撰写和/或发表本文的资金支持。
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