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疑似鞋类皮炎患者的斑贴试验:一项回顾性研究

Patch Testing in Patients with Suspected Footwear Dermatitis: A Retrospective Study.

作者信息

Garg Taru, Agarwal Soumya, Rana Shiwangi, Chander Ram

机构信息

Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi, India.

出版信息

Indian Dermatol Online J. 2017 Sep-Oct;8(5):323-327. doi: 10.4103/idoj.IDOJ_254_16.

DOI:10.4103/idoj.IDOJ_254_16
PMID:28979863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5621190/
Abstract

BACKGROUND

Footwear dermatitis represents a common but often undiagnosed or misdiagnosed condition. Patch testing aids in its confirmation and identification of the offending allergen.

AIMS

This study aimed to find the frequency of positive patch test reactions in cases with suspected allergic contact dermatitis (ACD) to footwear, as well as the common responsible allergens.

MATERIALS AND METHODS

This is a retrospective record based study of 37 patients, with suspected ACD to footwear, who underwent patch testing with Indian standard series and Indian footwear series from July 2012 to July 2015.

RESULTS

The majority of patients (45.94%) belonged to the age group of 20-40 years. Dorsal aspects of feet (81.08%) and soles (18.92%) were the common sites involved. Patch test was positive in 18.92% patients. The most common causative allergens were hydroquinone monobenzylether (8.11%) and 4-aminoazobenzene (5.41%).

CONCLUSION

Common chemicals implicated in ACD were rubber, rubber additives, and dyes. The principal culprit allergens were hydroquinone monobenzylether and 4-aminoazobenzene.

摘要

背景

鞋类皮炎是一种常见但常未被诊断或误诊的疾病。斑贴试验有助于确诊并识别致病过敏原。

目的

本研究旨在确定疑似鞋类过敏性接触性皮炎(ACD)病例中斑贴试验阳性反应的频率,以及常见的致病过敏原。

材料与方法

这是一项基于回顾性记录的研究,对2012年7月至2015年7月期间37例疑似鞋类ACD患者进行了印度标准系列和印度鞋类系列的斑贴试验。

结果

大多数患者(45.94%)年龄在20至40岁之间。足部背侧(81.08%)和足底(18.92%)是常见受累部位。18.92%的患者斑贴试验呈阳性。最常见的致病过敏原是对苯二酚单苄醚(8.11%)和4-氨基偶氮苯(5.41%)。

结论

与ACD相关的常见化学物质是橡胶、橡胶添加剂和染料。主要的致病过敏原是对苯二酚单苄醚和4-氨基偶氮苯。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/5ca8d7264408/IDOJ-8-323-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/26dc50c89e85/IDOJ-8-323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/ffdec226487d/IDOJ-8-323-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/5ca8d7264408/IDOJ-8-323-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/26dc50c89e85/IDOJ-8-323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/ffdec226487d/IDOJ-8-323-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b3/5621190/5ca8d7264408/IDOJ-8-323-g005.jpg

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本文引用的文献

1
Shoe allergic contact dermatitis.鞋类过敏性接触性皮炎
Dermatitis. 2014 Jul-Aug;25(4):163-71. doi: 10.1097/DER.0000000000000049.
2
Epidemio-allergological study in 155 cases of footwear dermatitis.155例鞋类皮炎的流行病学-变应性学研究
Indian J Dermatol Venereol Leprol. 2007 Sep-Oct;73(5):319-22. doi: 10.4103/0378-6323.34011.
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Patch testing experience with 1000 patients.对1000名患者进行斑贴试验的经验。
Indian J Dermatol Venereol Leprol. 2007 Sep-Oct;73(5):313-8. doi: 10.4103/0378-6323.34008.
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The relation between the localization of foot dermatitis and the causative allergens in shoes: a 13-year retrospective study.足部皮炎的发病部位与鞋类中致病过敏原之间的关系:一项13年的回顾性研究。
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Shoe dermatitis.
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Sensitivity to topical medicaments among suspected cases of footwear dermatitis.疑似鞋类皮炎病例对局部用药的敏感性。
Contact Dermatitis. 1993 Jan;28(1):44-5. doi: 10.1111/j.1600-0536.1993.tb03331.x.
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Footwear dermatitis.足部皮炎
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