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疑似化妆品皮炎患者的斑贴试验:一项回顾性研究。

Patch testing in patients with suspected cosmetic dermatitis: A retrospective study.

作者信息

Garg Taru, Agarwal Soumya, Chander Ram, Singh Aashim, Yadav Pravesh

机构信息

Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi, India.

出版信息

J Cosmet Dermatol. 2018 Feb;17(1):95-100. doi: 10.1111/jocd.12359. Epub 2017 Jun 1.

Abstract

BACKGROUND

Growing use of cosmetics has led to an increase in the incidence of allergic contact dermatitis (ACD) to cosmetics. Patch testing helps to confirm allergy to cosmetics and pinpoint the exact offending allergens.

AIMS AND OBJECTIVES

The study aimed to find the frequency of positive patch test reactions in cases with suspected ACD to cosmetics, and the common allergens responsible for it.

METHODS

This is a retrospective record-based study of 58 patients, with suspected ACD to cosmetics, who had undergone patch testing with Indian standard series and Indian cosmetic and fragrance series from January 2013 to December 2015.

RESULTS

The majority of patients (60.34%) belonged to the age group of 20-40 years. The most common site of involvement was face (94.8%) followed by neck (22.4%). The most commonly implicated cosmetics in history were soaps (53.4%), and face creams (24.1%). The most common allergens detected on patch testing were cetrimide (20.7%) and thimerosal (15.5%) followed by paraphenylenediamine (6.9%), and fragrance mix (5.2). Positive allergic reactions were obtained in 2.12% of the patches.

CONCLUSION

Most common cosmetic products implicated for causing ACD were face creams, soaps, and hair dyes. The principal culprit allergens were cetrimide and thimerosal.

摘要

背景

化妆品使用的增加导致化妆品过敏性接触性皮炎(ACD)的发病率上升。斑贴试验有助于确认对化妆品的过敏反应并找出确切的致病过敏原。

目的

本研究旨在确定疑似化妆品引起的ACD病例中斑贴试验阳性反应的频率以及相关的常见过敏原。

方法

这是一项基于回顾性记录的研究,研究对象为58例疑似化妆品引起的ACD患者,这些患者在2013年1月至2015年12月期间接受了印度标准系列以及印度化妆品和香料系列的斑贴试验。

结果

大多数患者(60.34%)年龄在20至40岁之间。最常受累的部位是面部(94.8%),其次是颈部(22.4%)。病史中最常涉及的化妆品是肥皂(53.4%)和面霜(24.1%)。斑贴试验中检测到的最常见过敏原是西曲溴铵(20.7%)和硫柳汞(15.5%),其次是对苯二胺(6.9%)和香料混合物(5.2%)。2.12%的斑贴出现阳性过敏反应。

结论

导致ACD的最常见化妆品是面霜、肥皂和染发剂。主要的致病过敏原是西曲溴铵和硫柳汞。

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