Chávez Karla V, Márquez-González Horacio, Aguirre Itzé, Orellana Juan C
Endoscopic Surgery Department, Hospital General "Dr. Manuel Gea González", Calzada de Tlalpan 4800, Tlalpan, PO Box 14000, Mexico City, Mexico.
Congenital Heart Disease Department, Hospital de Cardiología Centro Médico Nacional "Siglo XXI", Mexico City, Mexico.
Updates Surg. 2018 Mar;70(1):67-72. doi: 10.1007/s13304-017-0494-0. Epub 2017 Oct 4.
Laparoscopic cholecystectomy (LC) is the gold standard technique for the treatment of gallbladder disease. However, in some cases, conversion to open surgery is still necessary. Identification of patients with high risk of conversion is of great importance to prepare the surgical scenario and to anticipate the convalescence. The objective of this study is to identify the factors that may predict a conversion to an open procedure. A total of 1386 LC were performed in Dr. Manuel Gea González General Hospital, from January 2009 to May 2013. A retrospective analysis of 41 parameters in these patients was performed, including demographic variables, clinical history, laboratory studies, ultrasound results and intraoperative findings. Subsequently, a multivariate logistic regression analysis was used to determine the predictive variables for conversion. Fourteen patients required conversion (1%). The multivariate analysis revealed that the factor that was most associated with conversion was emergency surgery (OR 4.9, CI 95% 2.3-2.4), as well as dilatation > 6 mm of the common bile duct in ultrasound (OR 1.8, CI 95% 1.1-1.7), hepatomegaly (OR 1.3, CI 95% 0.3-4.9), diagnosis of chronic cholecystitis associated to previous biliary colics (OR 2.8, CI 95% 1.0-21) and elevated alanine aminotransaminase (OR 1.2, CI 95% 1.0-2.1). Patients with acute symptoms, with dilatation of the bile duct, cholestasis history and hepatomegaly have a higher risk of a conversion surgery. These factors may warn both the patient and the surgeon for a complex surgery and possible complications.
腹腔镜胆囊切除术(LC)是治疗胆囊疾病的金标准技术。然而,在某些情况下,仍有必要转为开腹手术。识别具有高转换风险的患者对于准备手术方案和预测康复情况非常重要。本研究的目的是确定可能预测转为开腹手术的因素。2009年1月至2013年5月,曼努埃尔·盖亚·冈萨雷斯博士综合医院共进行了1386例LC手术。对这些患者的41项参数进行了回顾性分析,包括人口统计学变量、临床病史、实验室检查、超声结果和术中发现。随后,采用多因素逻辑回归分析来确定转换的预测变量。14例患者需要转为开腹手术(1%)。多因素分析显示,与转换最相关的因素是急诊手术(比值比4.9,95%可信区间2.3 - 2.4),以及超声检查中胆总管扩张>6mm(比值比1.8,95%可信区间1.1 - 1.7)、肝肿大(比值比1.3,95%可信区间0.3 - 4.9)、与既往胆绞痛相关的慢性胆囊炎诊断(比值比2.8,95%可信区间1.0 - 21)和丙氨酸氨基转移酶升高(比值比1.2,95%可信区间1.0 - 2.1)。有急性症状、胆管扩张、胆汁淤积病史和肝肿大的患者进行转换手术的风险更高。这些因素可能会提醒患者和外科医生注意手术的复杂性和可能的并发症。