Department of Animal and Poultry Sciences, College of Abouraihan, University of Tehran, P.O. Box 11365-4117, Tehran, Iran.
Environ Sci Pollut Res Int. 2017 Dec;24(35):27484-27489. doi: 10.1007/s11356-017-0345-z. Epub 2017 Oct 4.
The objective of the present experiment was to investigate the effect of bentonite supplementation in lead (Pb)-exposed lambs on serum Pb, Ca, P, Cu, Zn, and Fe concentrations, blood hematological parameters, and hepatic enzymes. Twenty Zandi male lambs (initial BW, 17.5 ± 1.6 kg) were randomly assigned to one of the four treatments: (1) control (no Pb or bentonite), (2) 15 mg/kg DM Pb as Pb acetate with no bentonite, (3) 15 mg/kg DM Pb as Pb acetate with 1.5% bentonite, and (4) 15 mg/kg DM Pb as Pb acetate with 3% bentonite. The experiment lasted after 90 days. Lead intake resulted in a decrease (P < 0.05) in serum Fe and an increase in serum Pb, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) activities (P < 0.05). Bentonite supplementation at 1.5 or 3% of DM decreased blood Pb concentration (P < 0.01) in lambs fed diets containing Pb and reduced (P < 0.05) blood concentration of Cu and Zn compared to control group (P < 0.01). However, the hematological parameters were not affected by any of the treatments. Our results showed that the dietary supplementation of bentonite could protect lambs against lead toxicity.
本实验的目的是研究膨润土对铅暴露羔羊血清铅、钙、磷、铜、锌和铁浓度、血液血液学参数和肝脏酶的影响。20 只宰前重为 17.5±1.6kg 的雄性藏绵羊随机分为 4 个处理组：（1）对照组（无铅和膨润土）、（2）15mg/kg DM 乙酸铅+无膨润土、（3）15mg/kg DM 乙酸铅+1.5%膨润土、（4）15mg/kg DM 乙酸铅+3%膨润土。实验持续 90 天。铅的摄入导致血清铁含量降低（P<0.05），血清铅、天门冬氨酸氨基转移酶（AST）和丙氨酸氨基转移酶（ALT）活性升高（P<0.05）。在含有铅的日粮中添加 1.5%或 3%的膨润土，降低了羔羊的血液铅浓度（P<0.01），并降低了铜和锌的血液浓度（P<0.05），与对照组相比（P<0.01）。然而，血液学参数不受任何处理的影响。我们的结果表明，日粮中添加膨润土可以保护羔羊免受铅毒性的影响。
