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手性铑催化的芳基硼酸、1,3-烯炔和亚胺的对映选择性偶联反应：通过烯基到烯丙基 1,4-铑（I）迁移。

Enantioselective Rhodium-Catalyzed Coupling of Arylboronic Acids, 1,3-Enynes, and Imines by Alkenyl-to-Allyl 1,4-Rhodium(I) Migration.

机构信息

School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

The GSK Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Jubilee Campus, Triumph Road, Nottingham, NG7 2TU, UK.

出版信息

Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16352-16356. doi: 10.1002/anie.201709334. Epub 2017 Nov 24.

DOI:10.1002/anie.201709334
PMID:28980437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5765452/
Abstract

A chiral rhodium complex catalyzes the highly enantioselective coupling of arylboronic acids, 1,3-enynes, and imines to give homoallylic sulfamates. The key step is the generation of allylrhodium(I) species by alkenyl-to-allyl 1,4-rhodium(I) migration.

摘要

手性铑配合物催化芳基硼酸、1,3-二炔和亚胺的高对映选择性偶联反应，生成同烯丙基砜。关键步骤是通过烯丙基到烯丙基 1,4-铑（I）迁移生成烯丙基铑（I）物种。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/0fa6a22b93f2/ANIE-56-16352-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/86c61a8ad59a/ANIE-56-16352-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/68f2699d2772/ANIE-56-16352-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/9c7e87ff84f4/ANIE-56-16352-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/86daf6a38550/ANIE-56-16352-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/0fa6a22b93f2/ANIE-56-16352-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/86c61a8ad59a/ANIE-56-16352-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/68f2699d2772/ANIE-56-16352-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/9c7e87ff84f4/ANIE-56-16352-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/86daf6a38550/ANIE-56-16352-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e24a/5765452/0fa6a22b93f2/ANIE-56-16352-g005.jpg

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