Sakamaki Jun-Ichi, Long Jaclyn S, New Maria, Van Acker Tim, Tooze Sharon A, Ryan Kevin M
a Cancer Research UK Beatson Institute, Garscube Estate , Glasgow , UK.
b Molecular Cell Biology of Autophagy , Francis Crick Institute , London , UK.
Transcription. 2018;9(2):131-136. doi: 10.1080/21541264.2017.1372045. Epub 2017 Nov 3.
Autophagy is an essential cellular process that degrades cytoplasmic organelles and components. Precise control of autophagic activity is achieved by context-dependent signaling pathways. Recent studies have highlighted the involvement of transcriptional programs during autophagic responses to various signals. Here, we summarize the current understanding of the transcriptional regulation of autophagy.
自噬是一种重要的细胞过程，可降解细胞质细胞器和成分。自噬活性的精确控制是通过依赖于环境的信号通路实现的。最近的研究强调了转录程序在对各种信号的自噬反应中的作用。在这里，我们总结了目前对自噬转录调控的理解。
