Medley G F, Billard L, Cox D R, Anderson R M
Department of Biology, Imperial College, University of London, U.K.
Proc R Soc Lond B Biol Sci. 1988 Apr 22;233(1272):367-77. doi: 10.1098/rspb.1988.0026.
This paper contains details of methods and full results of estimates of the incubation period of acquired immunodeficiency syndrome (AIDS) that were outlined in a previous paper by Medley et al. (Nature, Lond. 328, 719 (1987)). The original model is modified to assess the influence of age and sex on the incubation period: age, but not sex, is statistically significant. The difficulties associated with interpretation of these data, and the additional information that would be required to resolve these difficulties are discussed.
本文包含了获得性免疫缺陷综合征(艾滋病)潜伏期估计方法的详细信息及完整结果,这些内容在Medley等人先前发表于《自然》(伦敦,第328卷,第719页,1987年)的一篇论文中已有概述。对原始模型进行了修改,以评估年龄和性别对潜伏期的影响:结果表明,年龄具有统计学意义,而性别没有。文中讨论了这些数据解读方面的困难,以及解决这些困难所需的额外信息。