Department of Physiology, Basic Medical College of Nanchang University, Nanchang 330006, China.
Acta Biochim Biophys Sin (Shanghai). 2017 Nov 1;49(11):967-972. doi: 10.1093/abbs/gmx083.
Catestatin (CST) is a neuroendocrine peptide which is derived from the chromogranin A. It has been demonstrated that CST can affect a wide range of processes, such as innate immunity, inflammatory and autoimmune reactions, and several homeostatic regulations. Furthermore, CST is positive against several kinds of bacterial strains at micromolecular range, which shows its antimicrobial activity. Recently, the role of CST in acute and chronic pain has attracted much attention. In this review, we discussed the latest research findings of CST and its role in innate immunity and pain.
缩胆囊素（CST）是一种神经内分泌肽，来源于嗜铬粒蛋白 A。已经证实 CST 可以影响广泛的过程，如先天免疫、炎症和自身免疫反应以及几种体内平衡调节。此外，CST 在微观范围内对多种细菌菌株呈阳性，显示出其抗菌活性。最近，CST 在急性和慢性疼痛中的作用引起了广泛关注。在这篇综述中，我们讨论了 CST 的最新研究结果及其在先天免疫和疼痛中的作用。
