Amo Carlos, De Santiago Luis, Zarza Luciáñez Daniel, León Alonso-Cortés José Miguel, Alonso-Alonso Miguel, Barea Rafael, Boquete Luciano
Department of Electronics, Universidad de Alcalá, Alcalá de Henares, Spain.
Research Department-Clinical Neurophysiology, Ecnis-Sigma SL, Madrid, Spain.
PLoS One. 2017 Oct 5;12(10):e0186008. doi: 10.1371/journal.pone.0186008. eCollection 2017.
The aim of this study was proposing gamma band activity (GBA) as an index of training-related brain plasticity in the motor cortex. Sixteen controls underwent an experimental session where electroencephalography (EEG) activity was recorded at baseline (resting) and during a motor task (hand movements). GBA was obtained from the EEG data at baseline and during the task. Index of plasticity (IP) was defined as the relationship between GBA at the end of the motor task (GBAM_FIN), divided by GBA at the beginning of the task (GBAM_INI) for movements of both hands. There was a significant increase in GBA at the end of the task, compared to the initial GBA for the motor task (GBAM_FIN > GBAM_INI). No differences were found at baseline (GBAB_FIN ≈ GBAB_INI). Individual IP values had a positive (r = 0.624) and significant correlation with subject's handedness. Due to plastic changes, GBA could indirectly but objectively reveal changes in cerebral activity related to physical training. This method could be used as a future diagnostic test in the follow-up of patients undergoing rehabilitation. It could also have potential applications in the fields of sports medicine.
本研究的目的是提出将伽马波段活动（GBA）作为运动皮层中与训练相关的脑可塑性指标。16名对照组人员参加了一次实验，期间记录了他们在基线（静息）状态和运动任务（手部运动）期间的脑电图（EEG）活动。GBA是从基线和任务期间的EEG数据中获得的。可塑性指数（IP）定义为双手运动时运动任务结束时的GBA（GBAM_FIN）除以任务开始时的GBA（GBAM_INI）。与运动任务初始时的GBA相比，任务结束时的GBA有显著增加（GBAM_FIN > GBAM_INI）。在基线时未发现差异（GBAB_FIN ≈ GBAB_INI）。个体IP值与受试者的利手呈正相关（r = 0.624）且具有显著相关性。由于可塑性变化，GBA可以间接但客观地揭示与体育训练相关的大脑活动变化。这种方法可作为未来对康复患者进行随访的诊断测试。它在运动医学领域也可能有潜在应用。
