Odoyo-June Elijah, Agot Kawango, Grund Jonathan M, Onchiri Frankline, Musingila Paul, Mboya Edward, Emusu Donath, Onyango Jacob, Ohaga Spala, Soo Leonard, Otieno-Nyunya Boaz
Division of Global HIV & TB (DGHT), U.S. Centers for Disease Control and Prevention (CDC), Nairobi, Kenya.
Impact Research and Development Organization, Kisumu, Kenya.
PLoS One. 2017 Oct 5;12(10):e0185872. doi: 10.1371/journal.pone.0185872. eCollection 2017.
Uptake of voluntary medical male circumcision (VMMC) as an intervention for prevention of HIV acquisition has been low among men aged ≥25 years in Nyanza region, western Kenya. We conducted a baseline survey of the prevalence and predictors of VMMC among men ages 25-39 years as part of the preparations for a cluster randomized controlled trial (cRCT) called the Target, Speed and Coverage (TASCO) Study. The TASCO Study aimed to assess the impact of two demand creation interventions-interpersonal communication (IPC) and dedicated service outlets (DSO), delivered separately and together (IPC + DSO)-on VMMC uptake.
As part of the preparatory work for implementation of the cRCT to evaluate tailored interventions to improve uptake of VMMC, we conducted a survey of men aged 25-39 years from a traditionally non-circumcising Kenyan ethnic community within non-contiguous locations selected as study sites. We determined their circumcision status, estimated the baseline circumcision prevalence and assessed predictors of being circumcised using univariate and multivariate logistic regression.
A total of 5,639 men were enrolled of which 2,851 (50.6%) reported being circumcised. The odds of being circumcised were greater for men with secondary education (adjusted Odds Ratio (aOR) = 1.65; 95% CI: 1.45-1.86, p<0.001), post-secondary education (aOR = 1.72; 95% CI: 1.44-2.06, p <0.001), and those employed (aOR = 1.32; 95% CI: 1.18-1.47, p <0.001). However, the odds were lower for men with a history of being married (currently married, divorced, separated, or widowed).
Among adult men in the rural Nyanza region of Kenya, men with post-primary education and employed were more likely to be circumcised. VMMC programs should focus on specific sub-groups of men, including those aged 25-39 years who are married, divorced/separated/ widowed, and of low socio-economic status (low education and unemployed).
在肯尼亚西部的尼扬扎地区,年龄≥25岁的男性中,自愿接受男性包皮环切术(VMMC)作为预防艾滋病毒感染干预措施的接受率较低。作为一项名为“目标、速度和覆盖范围(TASCO)研究”的整群随机对照试验(cRCT)筹备工作的一部分,我们对25至39岁男性中VMMC的患病率及预测因素进行了基线调查。TASCO研究旨在评估两种需求创造干预措施——人际沟通(IPC)和专用服务网点(DSO),单独实施以及联合实施(IPC + DSO)——对VMMC接受率的影响。
作为实施cRCT以评估针对性干预措施以提高VMMC接受率筹备工作的一部分,我们对来自肯尼亚一个传统上不进行包皮环切的民族社区、位于非相邻地点且被选为研究地点的25至39岁男性进行了调查。我们确定了他们的包皮环切状况,估计了基线包皮环切患病率,并使用单变量和多变量逻辑回归评估了接受包皮环切的预测因素。
共招募了5639名男性,其中2851名(50.6%)报告已接受包皮环切。接受过中等教育的男性接受包皮环切的几率更高(调整后的优势比(aOR)= 1.65;95%置信区间:1.45 - 1.86,p<0.001),接受过高等教育的男性(aOR = 1.72;95%置信区间:1.44 - 2.06,p <0.001)以及就业男性(aOR = 1.32;95%置信区间:1.18 - 1.47,p <0.001)。然而,有婚姻史(目前已婚、离婚、分居或丧偶)的男性接受包皮环切的几率较低。
在肯尼亚农村尼扬扎地区的成年男性中,接受过小学以上教育且就业的男性更有可能接受包皮环切。VMMC项目应关注特定的男性亚群体,包括年龄在25至39岁、已婚、离婚/分居/丧偶且社会经济地位较低(低教育水平和失业)的男性。