Akullian Adam, Onyango Mathews, Klein Daniel, Odhiambo Jacob, Bershteyn Anna
aInstitute for Disease Modeling, Bellevue, WA bNational AIDS and STI Control Program (NASCOP), Nairobi, Kenya.
Medicine (Baltimore). 2017 Jan;96(2):e5885. doi: 10.1097/MD.0000000000005885.
Voluntary Medical Male Circumcision (VMMC) for human immunodeficiency virus (HIV) prevention has scaled up rapidly among young men in western Kenya since 2008. Whether the program has successfully reached uncircumcised men evenly across the region is largely unknown. Using data from two cluster randomized surveys from the 2008 and 2014 Kenyan Demographic Health Survey (KDHS), we mapped the continuous spatial distribution of circumcised men by age group across former Nyanza Province to identify geographic areas where local circumcision prevalence is lower than the overall, regional prevalence. The prevalence of self-reported circumcision among men 15 to 49 across six counties in former Nyanza Province increased from 45.6% (95% CI = 33.2-58.0%) in 2008 to 71.4% (95% CI = 67.4-75.0%) in 2014, with the greatest increase in men 15 to 24 years of age, from 40.4% (95% CI = 27.7-55.0%) in 2008 to 81.6% (95% CI = 77.2-85.0%) in 2014. Despite the dramatic scale-up of VMMC in western Kenya, circumcision coverage in parts of Kisumu, Siaya, and Homa Bay counties was lower than expected (P < 0.05), with up to 50% of men aged 15 to 24 still uncircumcised by 2014 in some areas. The VMMC program has proven successful in reaching a large population of uncircumcised men in western Kenya, but as of 2014, pockets of low circumcision coverage still existed. Closing regional gaps in VMMC prevalence to reach 80% coverage may require targeting specific areas where VMMC prevalence is lower than expected.
自2008年以来,为预防人类免疫缺陷病毒(HIV)而开展的男性自愿包皮环切术(VMMC)在肯尼亚西部的年轻男性中迅速推广。该项目是否已成功在整个地区均匀覆盖未接受包皮环切术的男性,目前很大程度上尚不清楚。利用2008年和2014年肯尼亚人口与健康调查(KDHS)两次整群随机调查的数据,我们绘制了前尼扬扎省各年龄组接受包皮环切术男性的连续空间分布,以确定当地包皮环切术患病率低于总体区域患病率的地理区域。前尼扬扎省六个县15至49岁男性自我报告的包皮环切术患病率从2008年的45.6%(95%CI = 33.2 - 58.0%)增至2014年的71.4%(95%CI = 67.4 - 75.0%),其中15至24岁男性增幅最大,从2008年的40.4%(95%CI = 27.7 - 55.0%)增至2014年的81.6%(95%CI = 77.2 - 85.0%)。尽管肯尼亚西部的VMMC项目规模大幅扩大,但基苏木、锡亚和霍马湾县部分地区的包皮环切术覆盖率低于预期(P < 0.05),到2014年,一些地区15至24岁的男性中仍有高达50%未接受包皮环切术。事实证明,VMMC项目成功覆盖了肯尼亚西部大量未接受包皮环切术的男性,但截至2014年,仍存在包皮环切术覆盖率较低的地区。缩小VMMC患病率的区域差距以达到80%的覆盖率,可能需要针对VMMC患病率低于预期的特定地区。