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牙科X射线会诱发口腔黏膜细胞的基因毒性和细胞毒性吗?一项批判性综述。

Do Dental X-Rays Induce Genotoxicity and Cytotoxicity in Oral Mucosa Cells? A Critical Review.

作者信息

Angelieri Fernanda, Yujra Veronica Quispe, Oshima Celina Tizuko Fujiyama, Ribeiro Daniel Araki

机构信息

School of Dentistry, University of Guarulhos, Sao Paulo, Brazil.

Department of Pathology, Federal University of Sao Paulo, UNIFESP, Sao Paulo, Brazil.

出版信息

Anticancer Res. 2017 Oct;37(10):5383-5388. doi: 10.21873/anticanres.11964.

Abstract

Dental X-rays are widely used in clinical practice, since the technique is an important approach for diagnosing diseases in dental and periodontal tissues. However, it is widely known that radiation is capable of causing damage to cellular systems, such as genotoxicity or cytotoxicity. Thus, the aim of this review was to present a critical analysis regarding the studies published on genotoxicity and cytotoxicity induced by dental X-rays in oral mucosa cells. Such studies have revealed that some oral cell types are more sensitive than others following exposure to dental X-rays. Certainly, this review will contribute to a better understanding of this matter as well as to highlighting perspectives for further studies. Ultimately, such data will promote better safety for both patients and dental professionals.

摘要

牙科X射线在临床实践中被广泛应用,因为该技术是诊断牙齿和牙周组织疾病的重要方法。然而,众所周知,辐射能够对细胞系统造成损害,如基因毒性或细胞毒性。因此,本综述的目的是对已发表的关于牙科X射线在口腔黏膜细胞中诱导的基因毒性和细胞毒性的研究进行批判性分析。这些研究表明,某些口腔细胞类型在暴露于牙科X射线后比其他细胞类型更敏感。当然,本综述将有助于更好地理解这一问题,并突出进一步研究的方向。最终,这些数据将提高患者和牙科专业人员的安全性。

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