ST段抬高型心肌梗死极年轻患者的危险因素、临床表现及院内事件分析
Analysis of risk factors, presentation, and in-hospital events of very young patients presenting with ST-elevation myocardial infarction.
作者信息
Callachan Edward L, Alsheikh-Ali Alawi A, Wallis Lee A
机构信息
University of Cape Town, Division of Emergency Medicine, Belleville, South AfricaaSouth Africa.
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab EmiratesbUnited Arab Emirates.
出版信息
J Saudi Heart Assoc. 2017 Oct;29(4):270-275. doi: 10.1016/j.jsha.2017.01.004. Epub 2017 Feb 5.
INTRODUCTION
In the Indian subcontinent and Arab Gulf, coronary artery disease is affecting younger persons at greater rates. Few studies have focused on young ST-elevation myocardial infarction (STEMI) patients in these regions. We examine the clinical profile and treatment of STEMI patients aged <40 years.
METHODS
Participants consisted of 77 STEMI patients, aged <40 years, admitted to hospitals in Abu Dhabi. Data were collected using electronic medical records. Descriptive statistics were calculated for STEMI profile, medical history, risk factors, in-hospital events, and treatment.
RESULTS
Smoking was prevalent (61.0%). Beta blockers were frequently prescribed (90.7%); aspirin infrequently (12%). Of patients without history of each condition, 36.7% were diagnosed in-hospital with hypertension, 28.6% with elevated low-density lipoprotein, and 18.8% with lowered high-density lipoprotein.
CONCLUSIONS
Among young adults who use tobacco, there is a need for improved screening for risk factors. Earlier detection and treatment of dyslipidemia and hypertension could prevent acute cardiac events among individuals aged <40 years with multiple risk factors.
引言
在印度次大陆和阿拉伯海湾地区，冠状动脉疾病正以更高的发病率影响着年轻人。很少有研究关注这些地区的年轻ST段抬高型心肌梗死（STEMI）患者。我们研究了年龄小于40岁的STEMI患者的临床特征和治疗情况。
方法
参与者包括77名年龄小于40岁、入住阿布扎比医院的STEMI患者。通过电子病历收集数据。对STEMI特征、病史、危险因素、住院期间事件和治疗进行描述性统计。
结果
吸烟很普遍（61.0%）。β受体阻滞剂经常被处方（90.7%）；阿司匹林很少被处方（12%）。在没有每种疾病病史的患者中，36.7%在住院期间被诊断为高血压，28.6%被诊断为低密度脂蛋白升高，18.8%被诊断为高密度脂蛋白降低。
结论
在吸烟的年轻人中，需要改进对危险因素的筛查。早期发现和治疗血脂异常和高血压可以预防年龄小于40岁、有多种危险因素的个体发生急性心脏事件。
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