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爱尔兰中西部地区年轻患者ST段抬高型心肌梗死的相关危险因素:一项使用二手数据的病例系列报告

Risk factors associated with ST-segment elevation myocardial infarctions among young patients treated in the Mid-West of Ireland: a case series report using secondary data.

作者信息

Nantumbwe Sandra N, Gardiner Roisin, Kiernan Thomas J, Cummins Niamh M

机构信息

Faculty of Education and Health Sciences, School of Medicine, University of Limerick, Limerick, Ireland.

Health Research Institute, University of Limerick, Limerick, Ireland.

出版信息

Ir J Med Sci. 2025 May 29. doi: 10.1007/s11845-025-03965-w.

Abstract

BACKGROUND

ST-segment elevation myocardial infarction (STEMI) occurs when the myocardium has been damaged due to an acute occlusion of a coronary artery. STEMI commonly presents in older populations; however, little is known about the prevalence and risk factors among young patients. This is the first study on STEMI in young patients in Ireland.

AIMS

To determine the prevalence of STEMI and explore the associated risk factors in a cohort of young adults aged 45 years and below in the Mid-West of Ireland.

METHODS

This is a case series report using secondary data analysis of data collected from patients aged 45 years or below, hospitalized at University Hospital Limerick between January 2012 and December 2019. All patients who had a primary diagnosis of STEMI during this time period were eligible for inclusion. Clinical data were collected via electronic records and included demographic, clinical, and biomarker variables.

RESULTS

The sociodemographic characteristics of the STEMI patients revealed that a majority were male (90%), overweight or obese (63%), smokers (69%) and lived in urban areas (74%). Over half of the patients (53%) were diagnosed with hypertension, 69% had a family history of cardiovascular disease (CVD) and 40% had diabetes diagnosis. After initial hospitalization, 64% were readmitted for another procedure.

CONCLUSIONS

This study identified cardiovascular risk factors among STEMI patients in Ireland as male, smoking, family history of cardiovascular disease, and being overweight or obese. This study hopes to increase awareness of young STEMI patients and inform health promotion initiatives within this cohort.

摘要

背景

当冠状动脉急性闭塞导致心肌受损时,就会发生ST段抬高型心肌梗死(STEMI)。STEMI常见于老年人群;然而,对于年轻患者中的患病率和危险因素知之甚少。这是爱尔兰关于年轻患者STEMI的第一项研究。

目的

确定爱尔兰中西部45岁及以下年轻成年人队列中STEMI的患病率,并探讨相关危险因素。

方法

这是一篇病例系列报告,使用了对2012年1月至2019年12月期间在利默里克大学医院住院的45岁及以下患者收集的数据进行二次数据分析。在此期间所有初步诊断为STEMI的患者均符合纳入标准。临床数据通过电子记录收集,包括人口统计学、临床和生物标志物变量。

结果

STEMI患者的社会人口学特征显示,大多数为男性(90%)、超重或肥胖(63%)、吸烟者(69%)且居住在城市地区(74%)。超过一半的患者(53%)被诊断患有高血压,69%有心血管疾病(CVD)家族史,40%有糖尿病诊断。初次住院后,64%因再次手术而再次入院。

结论

本研究确定爱尔兰STEMI患者的心血管危险因素为男性、吸烟、心血管疾病家族史以及超重或肥胖。本研究希望提高对年轻STEMI患者的认识,并为该队列中的健康促进倡议提供信息。

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