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放射治疗在胸腺癌治疗中的地位与作用

The Place and the Role of Radiation Therapy in the Treatment of Thymic Carcinoma.

作者信息

Pinelopi-Theopisti Memtsa, Aikaterini Papadopoulou, Ariadni Kyriakogiannaki, Chrysoula Iliopoulou, Panagiotis Pantelis, Martha Charalambidou

机构信息

Department of Radiation Oncology, Cancer Hospital "Theageneio", Thessaloniki, Greece.

Department of Radiation Oncology, AHEPA Hospital, Aristotle University, Thessaloniki, Greece.

出版信息

World J Oncol. 2016 Dec;7(5-6):95-97. doi: 10.14740/wjon972e. Epub 2016 Dec 23.

DOI:10.14740/wjon972e
PMID:28983372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5624649/
Abstract

Thymic carcinomas arise from the epithelial cells of the thymus gland and are the most common tumors of the anterior mediastinum despite their overall rarity. Because of their rarity, their treatment remains a challenging topic. Although historically they have been treated surgically, radiation therapy (RT) has an important role either as a definitive or as a postoperative treatment. In this article, we present a review of the current therapies for the thymic carcinomas and try to identify the exact place of the RT in the optimal management of these patients.

摘要

胸腺癌起源于胸腺的上皮细胞,尽管总体上较为罕见,但却是前纵隔最常见的肿瘤。由于其罕见性,其治疗仍然是一个具有挑战性的话题。虽然历史上一直采用手术治疗,但放射治疗(RT)作为根治性治疗或术后治疗都发挥着重要作用。在本文中,我们对胸腺癌的当前治疗方法进行综述,并试图确定放射治疗在这些患者最佳管理中的确切地位。

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本文引用的文献

1
Postoperative radiotherapy for completely resected Masaoka stage III thymoma: a retrospective study of 65 cases from a single institution.完全切除的Masaoka III期胸腺瘤术后放疗:单机构65例回顾性研究
Radiat Oncol. 2013 Aug 13;8:199. doi: 10.1186/1748-717X-8-199.
2
Establishing locoregional control of malignant pleural mesothelioma using high-dose radiotherapy and (18) F-FDG PET/CT scan correlation.利用大剂量放疗及(18)F-FDG PET/CT扫描相关性建立恶性胸膜间皮瘤的局部区域控制。
J Med Imaging Radiat Oncol. 2011 Jun;55(3):320-32. doi: 10.1111/j.1754-9485.2011.02274.x.
3
Adjuvant radiotherapy for completely resected stage 2 thymoma.完全切除的 2 期胸腺瘤的辅助放疗。
Cancer. 2011 Aug 1;117(15):3502-8. doi: 10.1002/cncr.25851. Epub 2011 Feb 1.
4
Heart irradiation as a risk factor for radiation pneumonitis.心脏照射作为放射性肺炎的一个危险因素。
Acta Oncol. 2011 Jan;50(1):51-60. doi: 10.3109/0284186X.2010.521192. Epub 2010 Sep 28.
5
Technical advances of radiation therapy for thymic malignancies.胸腺癌放射治疗技术进展。
J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S336-43. doi: 10.1097/JTO.0b013e3181f20ea2.
6
Staging system of thymoma.胸腺瘤分期系统。
J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S304-12. doi: 10.1097/JTO.0b013e3181f20c05.
7
Epidemiology of thymoma and associated malignancies.胸腺瘤及相关恶性肿瘤的流行病学。
J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S260-5. doi: 10.1097/JTO.0b013e3181f1f62d.
8
The role of radiation therapy in malignant thymoma: a Surveillance, Epidemiology, and End Results database analysis.放疗在恶性胸腺瘤中的作用:一项监测、流行病学和最终结果数据库分析。
J Thorac Oncol. 2010 Sep;5(9):1454-60. doi: 10.1097/JTO.0b013e3181e8f345.
9
Prognostic indicators after surgery for thymoma.胸腺瘤手术后的预后指标。
Ann Thorac Surg. 2010 Apr;89(4):1071-7; discussion 1077-9. doi: 10.1016/j.athoracsur.2010.01.026.
10
Consequences of anatomic changes and respiratory motion on radiation dose distributions in conformal radiotherapy for locally advanced non-small-cell lung cancer.局部晚期非小细胞肺癌适形放疗中解剖学变化和呼吸运动对辐射剂量分布的影响
Int J Radiat Oncol Biol Phys. 2009 Jan 1;73(1):94-102. doi: 10.1016/j.ijrobp.2008.04.016. Epub 2008 Oct 17.