Miranda J A, Herruzo A J, Montoya F, Huete A, Mallol M C, Delaorden A F
Department of Obstetrics and Gynecology, Virgen de las Nieves Regional Hospital, Granada, Spain.
Int J Gynaecol Obstet. 1988 Apr;26(2):209-12. doi: 10.1016/0020-7292(88)90264-0.
This study examines whether labor can be induced with the intramuscular administration of 15-(S)-methyl prostaglandin F2 alpha in cases of intrauterine fetal death. The success rate of labor induction in the studied group was 93.75%, and was the same for primigravid and multigravid patients. The authors conclude that the prophylactic administration of an analgesic potentiator, an anti-emetic and an anti-diarrheal is advantageous to a woman's tolerance of the prostaglandin. PGF2 alpha is a quick and effective drug for use in the induction of labor to terminate pregnancies with intrauterine fetal death and offers tolerable side-effects when used with adjuvant medication.
本研究探讨在宫内死胎病例中,肌肉注射15 -(S)-甲基前列腺素F2α能否诱发宫缩。研究组的引产成功率为93.75%,初产妇和经产妇的成功率相同。作者得出结论,预防性给予止痛增效剂、止吐药和止泻药有利于提高女性对前列腺素的耐受性。PGF2α是一种快速有效的药物,用于引产以终止宫内死胎妊娠,与辅助药物联合使用时副作用可耐受。