Hjertkvist M, Bergh A, Damber J E
Department of Surgery, University of Umeå, Sweden.
J Androl. 1988 Mar-Apr;9(2):116-20. doi: 10.1002/j.1939-4640.1988.tb01021.x.
Adult, unilaterally cryptorchid rats were given a single subcutaneous injection of hCG. HCG treatment of 100 I.U. (but not 10 I.U.) resulted in a marked increase in intratesticular pressure (approximately 40 mm Hg) in the abdominal testis that was maximal 24 hours after treatment. This increase in pressure is caused by increased vascular permeability coupled with insufficient lymph drainage. In the scrotal testis, hCG treatment resulted in increased vascular permeability and lymph flow, but this did not result in a marked increase in testicular pressure. No morphologic signs of hCG-induced damage were observed in either the abdominal or scrotal testis 10 days after hCG treatment. Testicular microcirculation, as studied by laser doppler flowmetry, was abnormal in the abdominal testis, but hCG treatment inhibited vasomotion in both the abdominal and scrotal testis.
对成年单侧隐睾大鼠进行单次皮下注射人绒毛膜促性腺激素（hCG）。注射100国际单位（而非10国际单位）的hCG可使腹腔内睾丸的睾丸内压力显著升高（约40毫米汞柱），在治疗后24小时达到最大值。这种压力升高是由于血管通透性增加以及淋巴引流不足所致。在阴囊内睾丸中，hCG治疗导致血管通透性增加和淋巴流量增加，但这并未导致睾丸压力显著升高。在hCG治疗10天后，无论是腹腔内睾丸还是阴囊内睾丸，均未观察到hCG诱导损伤的形态学迹象。通过激光多普勒血流仪研究发现，腹腔内睾丸的睾丸微循环异常，但hCG治疗可抑制腹腔内和阴囊内睾丸的血管运动。
