Abdelnaby Elshymaa A, Alhaider Abdulrhman K, Emam Ibrahim A
Department of Clinical Sciences, College of Veterinary Medicine, King Faisal University, P.O. Box 400, Al-Ahsa, 31982, Saudi Arabia.
Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Vet Res Commun. 2025 Sep 5;49(5):301. doi: 10.1007/s11259-025-10852-3.
The current study aimed to determine the impacts of hCG injection on the reproductive performance and hormonal profile of senile camels. Ten adult senile camels were classified into two groups: control males (n = 5) and treated males (n = 5; received hCG) once/week. Testicular morphology and echotexture [testicular volume (TV), testicular echogenicity (TE), and pixel heterogeneity (PH)] were measured. Testicular blood flow (TBF), colored area (CA), testicular resistance and pulsatility indices (RI and PI), steroids [estradiol (E2) and testosterone (T), as well as nitric oxide (NO)] were estimated. Sperm motility [total motility (TM; %), non-progressive motility (NPM; %), progressive motility (PM; %)], sperm cell concentration (SCC; 10 /mL), and viability (V; %) were also estimated. Examination begins one week before injection (W-1) and continued from W0 till W8 and then continued until W12 to determine post-treatment effect. Significant elevation (P < 0.05) of both TBF and CA (pixels) from W5 to W9, while TE, PH, RI, and PI were significantly declined (P < 0.05) from W4 to W8. E2, T, and NO levels were elevated (P = 0.01) from W4 to W8 for E2 and T, and from W4 to W9 for NO. Significant (P = 0.02) elevation of TM%, V%, PM%, and SCC from W8 to W11, with a decline in NPM%. T, E2, and NO positively correlated with TBF and negatively correlated with RI and PI. In conclusion, repeated administration of hCG improved the reproductive performance of senile male camels with an alteration in semen quality, steroids, testicular artery blood flow pattern, and NO levels.
本研究旨在确定注射人绒毛膜促性腺激素（hCG）对老年骆驼繁殖性能和激素水平的影响。将10只成年老年骆驼分为两组：对照组雄性（n = 5）和治疗组雄性（n = 5；每周接受一次hCG注射）。测量睾丸形态和回声特征[睾丸体积（TV）、睾丸回声（TE）和像素异质性（PH）]。评估睾丸血流（TBF）、彩色区域（CA）、睾丸阻力和搏动指数（RI和PI）、类固醇[雌二醇（E2）和睾酮（T）以及一氧化氮（NO）]。还评估精子活力[总活力（TM；%）、非进行性活力（NPM；%）、进行性活力（PM；%）]、精子细胞浓度（SCC；10⁶/mL）和存活率（V；%）。检查在注射前一周（W - 1）开始，从W0持续到W8，然后持续到W12以确定治疗后的效果。从W5到W9，TBF和CA（像素）显著升高（P < 0.05），而从W4到W8，TE、PH、RI和PI显著下降（P < 0.05）。E2、T和NO水平在W4到W8期间E2和T升高（P = 0.01），在W4到W9期间NO升高。从W8到W11，TM%、V%、PM%和SCC显著升高（P = 0.02），NPM%下降。T、E2和NO与TBF呈正相关，与RI和PI呈负相关。总之，重复注射hCG改善了老年雄性骆驼的繁殖性能，同时精液质量、类固醇、睾丸动脉血流模式和NO水平发生了改变。
