Li-Beisson Yonghua, Neunzig Jens, Lee Youngsook, Philippar Katrin
CEA, CNRS and Aix-Marseille Université, Institut de Biosciences et Biotechnologies d'Aix-Marseille, UMR 7265, CEA Cadarache, Saint-Paul-lez Durance F-13108, France.
Saarland University, Center for Human- and Molecular Biology - Plant Biology, Campus A 2.4, D-66123 Saarbrücken, Germany.
Curr Opin Plant Biol. 2017 Dec;40:138-146. doi: 10.1016/j.pbi.2017.09.006. Epub 2017 Oct 3.
In plants, de novo synthesis of fatty acids (FAs) occurs in plastids, whereas assembly and modification of acyl lipids is accomplished in the endoplasmic reticulum (ER) and plastids as well as in mitochondria. Subsequently, lipophilic compounds are distributed within the cell and delivered to their destination site. Thus, constant acyl-exchanges between subcellular compartments exist. These can occur via several modes of transport and plant membrane-intrinsic proteins for FA/lipid transfer have been shown to play an essential role in delivery and distribution. Lately, substantial progress has been made in identification and characterization of transport proteins for lipid compounds in plant organelle membranes. In this review, we focus on our current understanding of protein mediated lipid traffic between organelles of land plants.
在植物中，脂肪酸（FAs）的从头合成发生在质体中，而酰基脂质的组装和修饰则在内质网（ER）、质体以及线粒体中完成。随后，亲脂性化合物在细胞内进行分布并被输送到其目的地。因此，亚细胞区室之间存在持续的酰基交换。这些交换可以通过几种运输方式发生，并且已证明植物膜内在蛋白在脂肪酸/脂质转运中起着至关重要的作用。最近，在植物细胞器膜中脂质化合物转运蛋白的鉴定和表征方面取得了重大进展。在本综述中，我们重点关注目前对陆地植物细胞器之间蛋白质介导的脂质运输的理解。
