Plummer Caryn E
Comparative Ophthalmology, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100101, 2015 Southwest 16th Avenue, Gainesville, FL 32610, USA; Comparative Ophthalmology, Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100101, 2015 Southwest 16th Avenue, Gainesville, FL 32610, USA.
Vet Clin North Am Equine Pract. 2017 Dec;33(3):439-463. doi: 10.1016/j.cveq.2017.07.002. Epub 2017 Oct 3.
This article describes the natural responses of the immune system and the cornea to injury and infection. The process of reepithelialization and reformation of stromal collagen is discussed, as are the clinical signs and manifestations of the effects of the healing response when it is routine and when it is pathologic. Excessive inflammatory or immune responses by host tissues can cause further damage that may be present from the antecedent injury or the effect of a pathogen. The clinical signs and manifestations of wound healing as well as potential therapeutic interventions are described.
本文描述了免疫系统和角膜对损伤及感染的自然反应。文中讨论了角膜上皮再生和基质胶原重塑的过程，以及愈合反应在正常和病理情况下的临床体征和表现。宿主组织过度的炎症或免疫反应会导致进一步损伤，这些损伤可能源于先前的损伤或病原体的影响。本文还描述了伤口愈合的临床体征和表现以及潜在的治疗干预措施。
