Vorrasi John S, Kolokythas Antonia
Department of Oral and Maxillofacial Surgery, University of Rochester Strong Memorial Hospital, Eastman Institute for Oral Health, 601 Elmwood Avenue, PO Box 705, Rochester, NY 14642, USA.
Department of Oral and Maxillofacial Surgery, University of Rochester Strong Memorial Hospital, Eastman Institute for Oral Health, 601 Elmwood Avenue, PO Box 705, Rochester, NY 14642, USA.
Oral Maxillofac Surg Clin North Am. 2017 Nov;29(4):401-413. doi: 10.1016/j.coms.2017.06.003.
Traditional reconstruction of the head and neck and significantly evolved over the last 20 to 30 years with advances in microvascular surgery, biologic materials such as bone morphogenic protein, and dental implant predictability. Earlier and more definitive reconstruction can now be achieved with combining therapies, allowing patients immediate restoration of function and improved cosmetics. Antiresorptive medications, such as Denosumab and bisphosphonates, have complicated bony reconstruction treatments with altered biology and less-predictable results. Virtual surgical planning is a major advancement for reconstruction pretreatment planning and designing of intraoperative tools to expedite the operation and achieve more predictable results.
传统的头颈部重建在过去20至30年中随着微血管外科手术、骨形态发生蛋白等生物材料以及牙种植可预测性的进展而显著发展。现在通过联合治疗可以实现更早、更确切的重建，使患者能够立即恢复功能并改善外观。抗吸收药物，如地诺单抗和双膦酸盐，因改变生物学特性和降低结果可预测性而使骨重建治疗变得复杂。虚拟手术规划是重建术前规划和术中工具设计的一项重大进展，有助于加快手术进程并获得更可预测的结果。
