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手术时间对成人脊柱畸形手术后30天并发症的影响。

Impact of Operation Time on 30-Day Complications After Adult Spinal Deformity Surgery.

作者信息

Phan Kevin, Kim Jun S, Capua John Di, Lee Nathan J, Kothari Parth, Dowdell James, Overley Samuel C, Guzman Javier Z, Cho Samuel K

机构信息

University of New South Wales, Sydney, New South Wales, Australia.

Prince of Wales Private Hospital, Sydney, New South Wales, Australia.

出版信息

Global Spine J. 2017 Oct;7(7):664-671. doi: 10.1177/2192568217701110. Epub 2017 May 31.

Abstract

STUDY DESIGN

Retrospective analysis of prospectively collected data.

OBJECTIVE

There is a paucity of data on the effect of operative duration on postoperative complications during adult spinal deformity surgery (ASDS). The study attempts to explore and quantify the association between increased operation times and postoperative complications.

METHODS

A retrospective cohort analysis was performed on the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2010 to 2014. Patients (≥18 years of age) from the NSQIP database undergoing ASDS were separated into cohorts based on quartiles of operation duration. Chi-square and multivariate logistic regression models were used to identify risk factors.

RESULTS

A total of 5338 patients met the inclusion criteria and were divided per quartiles based on operative duration in minutes (154, 235, 346, and 1156 minutes). Multivariate logistic regressions revealed that in comparison to the lowest quartile of operative duration, the highest quartile group was associated significantly with length of stay ≥5 days (odds ratio [OR] = 5.85), any complication (OR = 9.88), wound complication (OR = 5.95), pulmonary complication (OR = 2.85, = .001), venous thromboembolism (OR = 12.37), intra-/postoperative transfusion (OR = 12.77), sepsis (OR = 5.27), reoperations (OR = 1.48), and unplanned readmissions (OR = 1.29). The odds ratio was higher when comparing a higher quartile group with the reference group across all associations. < .001 unless otherwise noted.

CONCLUSION

ASDS operation time is associated with multiple postoperative complications, including, but not limited to, wound and pulmonary complications, venous thromboembolism, postoperative transfusion, length of stay ≥5 days, sepsis, reoperation, and unplanned readmission.

摘要

研究设计

对前瞻性收集的数据进行回顾性分析。

目的

关于手术时长对成人脊柱畸形手术(ASDS)术后并发症影响的数据较少。本研究试图探究并量化手术时间延长与术后并发症之间的关联。

方法

对美国外科医师学会国家外科质量改进计划(ACS-NSQIP)2010年至2014年的数据库进行回顾性队列分析。将NSQIP数据库中接受ASDS的患者(≥18岁)根据手术时长四分位数分为不同队列。采用卡方检验和多因素逻辑回归模型来确定危险因素。

结果

共有5338例患者符合纳入标准,并根据手术时长(分钟)四分位数进行分组(154、235、346和1156分钟)。多因素逻辑回归显示,与手术时长最低四分位数组相比,最高四分位数组与住院时间≥5天(比值比[OR]=5.85)、任何并发症(OR=9.88)、伤口并发症(OR=5.95)、肺部并发症(OR=2.85,P=.001)、静脉血栓栓塞(OR=12.37)、术中和/或术后输血(OR=12.77)、败血症(OR=5.27)、再次手术(OR=1.48)及非计划再入院(OR=1.29)显著相关。在所有关联中,与参照组相比,较高四分位数组的比值比更高。P<.001,除非另有说明。

结论

ASDS手术时间与多种术后并发症相关,包括但不限于伤口和肺部并发症、静脉血栓栓塞、术后输血、住院时间≥5天、败血症、再次手术及非计划再入院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba30/5624378/09bae099c4ea/10.1177_2192568217701110-fig1.jpg

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