Lee Nathan J, Shin John I, Kothari Parth, Kim Jun S, Leven Dante M, Steinberger Jeremy, Guzman Javier Z, Skovrlj Branko, Caridi John M, Cho Samuel K
Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Global Spine J. 2017 Aug;7(5):417-424. doi: 10.1177/2192568217699378. Epub 2017 Apr 20.
Case-control study.
To determine the incidence, impact, and risk factors for wound complications within 30 days following elective adult spinal deformity surgery.
Current Procedural Terminology and International Classification of Diseases, Ninth Edition, diagnosis codes were used to query the database for adults who underwent spinal deformity surgery from 2010 to 2014. Patients were separated into groups of those with and without wound complications. Univariate analysis and multivariate logistic regression were used to analyze the influence of patient factors, operative variables, and clinical characteristics on the incidence of postoperative wound complication. This study was qualified as exempt by the Mount Sinai Hospital Institutional Review Board.
A total of 5803 patients met the criteria for this study. Wound complications occurred in 140 patients (2.4%) and were significantly associated with other adverse outcomes, including higher rates of unplanned reoperation ( < .0001) and prolonged length of stay ( < .0001). Regardless of fusion length, wound complication rates were higher with a posterior approach (short = 2.7%; long = 3.7%) than an anterior one (short = 2.2%; long = 2.7). According to the multivariate analysis, posterior fusion (odds ratio [OR] = 1.8; = .010), obese class II (OR = 1.7; = .046), obese class III (OR = 2.8; < .0001), preoperative blood transfusion (OR = 6.1; = .021), American Society of Anesthesiologists class ≥3 (OR = 1.7; = .009), and operative time >4 hours (OR = 1.8; = .006) were statistically significant risk factors for wound complications.
The 30-day incidence of wound complication in adult spinal deformity surgery is 2.4%. The risk factors for wound complication are multifactorial. This data should provide a step toward developing quality improvement measures aimed at reducing complications in high-risk adults.
病例对照研究。
确定择期成人脊柱畸形手术后30天内伤口并发症的发生率、影响及危险因素。
使用当前手术操作术语和国际疾病分类第九版诊断编码查询2010年至2014年接受脊柱畸形手术的成人数据库。患者被分为有伤口并发症组和无伤口并发症组。采用单因素分析和多因素逻辑回归分析患者因素、手术变量和临床特征对术后伤口并发症发生率的影响。本研究被西奈山医院机构审查委员会认定为豁免研究。
共有5803例患者符合本研究标准。140例患者(2.4%)发生伤口并发症,且与其他不良结局显著相关,包括计划外再次手术率更高(<0.0001)和住院时间延长(<0.0001)。无论融合长度如何,后路手术的伤口并发症发生率(短节段=2.7%;长节段=3.7%)高于前路手术(短节段=2.2%;长节段=2.7%)。根据多因素分析,后路融合术(优势比[OR]=1.8;P=0.010)、II级肥胖(OR=1.7;P=0.046)、III级肥胖(OR=2.8;P<0.0001)、术前输血(OR=6.1;P=0.021)、美国麻醉医师协会分级≥3级(OR=1.7;P=0.009)以及手术时间>4小时(OR=1.8;P=0.006)是伤口并发症的统计学显著危险因素。
成人脊柱畸形手术中伤口并发症的30天发生率为2.4%。伤口并发症的危险因素是多因素的。这些数据应为制定旨在降低高危成人并发症的质量改进措施迈出一步。