Gogia Sonalika, Rao Chythra R
Department of Community Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Indian J Endocrinol Metab. 2017 Sep-Oct;21(5):665-669. doi: 10.4103/ijem.IJEM_43_17.
In view of the growing burden of type 2 diabetes mellitus (T2DM) globally and associated microvascular and macrovascular complications, the study was done to assess the prevalence and risk factors for diabetic neuropathy among T2DM patients attending a tertiary care hospital.
T2DM patients' ≥30 years of both gender, presenting to the Medicine Department at a tertiary care hospital were included in the study. Diabetic Neuropathy Symptom (DNS) questionnaire to assess symptoms and Diabetic Neuropathy Examination (DNE) scoring to assess clinical signs were used.
A total of 273 patients were included. The mean age was 57.8 ± 11.5 years. The male to female distribution was 75% (202) and 25% (71), respectively. According to DNS instrument, 41.4% patients scored positive for the presence of neuropathy while only 24.5% had neuropathy according to DNE score. The proportion of males affected by neuropathy was more than females. 43.1% males had a positive DNS score while only 27.2% of them had a positive DNE score. Duration of the disease was positively correlated with neuropathy. Neuropathy was more prevalent among people who had higher systolic and diastolic blood pressure as per DNS and DNE instruments.
The present study identified a higher proportion of males to be affected by neuropathy. Hence, more detailed evaluation must be accorded to elderly male diabetic patients with longer duration of the disease. Lifestyle modifications and watchful screening need to be incorporated as part of routine patient health education during follow-up clinic visits.
鉴于全球2型糖尿病（T2DM）负担日益加重及其相关的微血管和大血管并发症，本研究旨在评估一家三级护理医院中T2DM患者糖尿病神经病变的患病率及危险因素。
纳入年龄≥30岁、在一家三级护理医院内科就诊的T2DM患者，无论性别。使用糖尿病神经病变症状（DNS）问卷评估症状，采用糖尿病神经病变检查（DNE）评分评估临床体征。
共纳入273例患者。平均年龄为57.8±11.5岁。男女分布分别为75%（202例）和25%（71例）。根据DNS工具，41.4%的患者神经病变评分为阳性，而根据DNE评分，只有24.5%的患者患有神经病变。男性受神经病变影响的比例高于女性。43.1%的男性DNS评分为阳性，而其中只有27.2%的男性DNE评分为阳性。病程与神经病变呈正相关。根据DNS和DNE工具，收缩压和舒张压较高的人群中神经病变更为普遍。
本研究发现男性受神经病变影响的比例更高。因此，对于病程较长的老年男性糖尿病患者，必须给予更详细的评估。在随访门诊期间，应将生活方式调整和密切筛查纳入常规患者健康教育的一部分。
