单胎妊娠与双胎妊娠晚期早产围产期结局的比较。
Comparison of perinatal outcomes in late preterm birth between singleton and twin pregnancies.
作者信息
Yoo Eun-Hye, Chun Dasom, Kim Mi Ju, Cha Hyun-Hwa, Seong Won Joon
机构信息
Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.
出版信息
Obstet Gynecol Sci. 2017 Sep;60(5):421-426. doi: 10.5468/ogs.2017.60.5.421. Epub 2017 Sep 18.
OBJECTIVE
To determine whether late preterm twin neonates have a more favorable perinatal outcome than singleton late preterm neonates.
METHODS
We studied 401 late preterm births between 34+0 and 36+6 weeks of gestation, from January 2011 to December 2014 in our institution. We compared the maternal and neonatal characteristics and perinatal outcomes between singleton and twin pregnancies. Perinatal outcomes included Apgar score, admission to the neonatal intensive care unit (NICU) or special care nursery, duration of NICU stay, and the rate of composite morbidity (antibiotic use, hypoglycemia, hypocalcemia, hyperbilirubinemia requiring phototherapy, respiratory support, and respiratory distress syndrome).
RESULTS
A total of 289 neonates were in the singleton group and 112 in the twin group. The twin group showed smaller mean birth weight despite of longer gestational age at delivery. In addition, there were significant differences in the indication of delivery and cesarean section rate between the 2 groups. Overall, the risk of composite morbidity was similar between 2 groups (odds ratio, 1.4; 95% confidence interval, 0.8 to 2.4).
CONCLUSION
Our findings suggest that late preterm twins do not show a more favorable outcome than singleton late preterm births.
目的
确定晚期早产双胎新生儿的围产期结局是否比晚期早产单胎新生儿更有利。
方法
我们研究了2011年1月至2014年12月在我院发生的401例孕34⁺⁰至36⁺⁶周的晚期早产分娩。我们比较了单胎和双胎妊娠的母体和新生儿特征以及围产期结局。围产期结局包括阿氏评分、入住新生儿重症监护病房（NICU）或特殊护理病房、NICU住院时间以及综合发病率（使用抗生素、低血糖、低钙血症、需要光疗的高胆红素血症、呼吸支持和呼吸窘迫综合征）。
结果
单胎组共有289例新生儿，双胎组有112例。双胎组尽管分娩时孕周较长，但平均出生体重较小。此外，两组之间的分娩指征和剖宫产率存在显著差异。总体而言，两组之间的综合发病风险相似（优势比，1.4；95%置信区间，0.8至2.4）。
结论
我们的研究结果表明，晚期早产双胎的结局并不比晚期早产单胎更有利。
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