Shmal'ko Iu P, Mikhaleva I I
Eksp Onkol. 1988;10(2):57-60.
The experiments on C57Bl mice with metastatic Lewis lung carcinoma have shown that peptide delta-sleep (DSIP) lowers the stimulation of metastatic spreading which is observed in combination of the surgical removal of the tumour with the emotional-painful stress. The antimetastatic effect is accompanied by stabilization of neurohumoral indices, by a decrease in the intensity of lipid peroxidation and of the acid cathepsin activity in the blood vessels and in the lung tissue.
对患有转移性Lewis肺癌的C57Bl小鼠进行的实验表明，δ-睡眠肽（DSIP）可降低在肿瘤手术切除与情感性疼痛应激相结合时所观察到的转移扩散刺激。抗转移作用伴随着神经体液指标的稳定、血管和肺组织中脂质过氧化强度以及酸性组织蛋白酶活性的降低。
