Department of Sustainable Agro-Ecosystems and Bioresources, Research and Innovation Centre, Fondazione Edmund Mach (FEM), San Michele all'Adige, Italy.
Department of Agricultural, Food, Environmental and Animal Sciences, PhD School in Agricultural Science and Biotechnology, University of Udine, Udine, Italy.
J Appl Microbiol. 2018 Jan;124(1):15-27. doi: 10.1111/jam.13607. Epub 2017 Nov 5.
Omics technologies have had a tremendous impact on underinvestigated genera of plant disease biocontrol agents such as Lysobacter. Strong evidence of the association between Lysobacter spp. and the rhizosphere has been obtained through culture-independent methods, which has also contributed towards highlighting the relationship between Lysobacter abundance and soil suppressiveness. It is conceivable that the role played by Lysobacter spp. in soil suppressiveness is related to their ability to produce an impressive array of lytic enzymes and antibiotics. Indeed, genomics has revealed that biocontrol Lysobacter strains share a vast number of genes involved in antagonism activities, and the molecular pathways underlying how Lysobacter spp. interact with the environment and other micro-organisms have been depicted through transcriptomic analysis. Furthermore, omics technologies shed light on the regulatory pathways governing cell motility and the biosynthesis of antibiotics. Overall, the results achieved so far through omics technologies confirm that the genus Lysobacter is a valuable source of novel biocontrol agents, paving the way for studies aimed at making their application in field conditions more reliable.
组学技术对植物病害生物防治剂（如Lysobacter）等研究较少的属产生了巨大影响。通过非培养方法获得了Lysobacter 属与根际之间存在关联的有力证据，这也有助于突出 Lysobacter 丰度与土壤抑制之间的关系。可以想象，Lysobacter 属在土壤抑制中的作用与其产生大量裂解酶和抗生素的能力有关。事实上，基因组学揭示了生物防治 Lysobacter 菌株共享大量参与拮抗活性的基因，通过转录组分析描绘了 Lysobacter 属与环境和其他微生物相互作用的分子途径。此外，组学技术揭示了调控细胞运动和抗生素生物合成的调控途径。总的来说，目前通过组学技术取得的成果证实，Lysobacter 属是新型生物防治剂的宝贵来源，为旨在提高其在田间条件下应用可靠性的研究铺平了道路。
