Department of Dermatology and Venereology, Ryhov County Hospital, Jönköping, Sweden.
Department of Dermatology and Venereology in Östergötland, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Acta Derm Venereol. 2024 Sep 5;104:adv40543. doi: 10.2340/actadv.v104.40543.
Hyperhidrosis is associated with social and emotional stress, affecting quality of life. Microwave energy technology treats primary axillary hyperhidrosis by thermolysis of sweat glands. The successful reduction of sweating in patients with primary axillary hyperhidrosis after microwave treatment has been studied, but there is limited evidence on the psychological and long-term effects. This study examined patient- reported outcome measures including depression and anxiety in patients with primary axillary hyperhidrosis and the effect of microwave therapy on these parameters. Patients received 1 or 2 microwave-based treatments, within 3-month intervals. All patients were finally examined at approximately 1 year after the first treatment using the Hyperhidrosis Disease Severity Scale, Hyperhidrosis Quality of Life©, Dermatology Life Quality Index, and Hospital Anxiety and Depression Scale©. A total of 103 individuals with primary axillary hyperhidrosis were included in the study, with a Hyperhidrosis Disease Severity Scale score of 3 or 4. Statistically significant improvement in quality of life, anxiety, and depression scores were observed at 1-year follow-up. The primary endpoint, Hyperhidrosis Disease Severity Scale of 2 or less 1 year after the first treatment, was achieved by 88.2% of patients. No serious adverse side effects were observed.
多汗症与社会和情绪压力有关，影响生活质量。微波能技术通过热解汗腺来治疗原发性腋窝多汗症。已经研究了微波治疗原发性腋窝多汗症患者减少出汗的效果，但关于心理和长期效果的证据有限。本研究通过患者报告的结果衡量指标，包括原发性腋窝多汗症患者的抑郁和焦虑，以及微波治疗对这些参数的影响。患者在 3 个月的间隔内接受 1 或 2 次微波治疗。所有患者在第一次治疗后约 1 年，使用多汗症疾病严重程度量表、多汗症生活质量量表、皮肤病生活质量指数和医院焦虑抑郁量表进行最终检查。共有 103 名原发性腋窝多汗症患者纳入研究，多汗症疾病严重程度量表评分为 3 或 4。在 1 年的随访中，观察到生活质量、焦虑和抑郁评分的显著改善。主要终点是第一次治疗后 1 年时多汗症疾病严重程度量表评分为 2 或更低，88.2%的患者达到了这一标准。未观察到严重的不良副作用。
