Srinivasan R, Kanungo R, Goyal J L
Department of Ophthalmology, Jawaharlal Institute of Post-Graduate Medical Education and Research, Pondicherry, India.
Acta Ophthalmol (Copenh). 1991 Dec;69(6):744-9. doi: 10.1111/j.1755-3768.1991.tb02053.x.
Ninety-one consecutive cases of proven oculomycosis were studied in relation to clinical features and epidemiological parameters. Mycotic corneal ulcers formed the major group (76%), followed by endophthalmitis (20%). Aspergillus was the common causative fungus (36%) in keratomycosis followed by Penicillium species (29%). Fusarium keratomycosis was not as common as reported in the literature. In endophthalmitis there was preponderance of Penicillium as the causative fungus. These etiological agents are studied in comparison with studies of conjunctival flora of healthy controls and culture studies of common objects of trauma. Mycotic endophthalmitis was seen following cataract surgery in 64% of cases. Contrary to expectations the onset of endophthalmitis was within 2 weeks of surgery in most cases. Trauma with organic matter was an important predisposing factor in keratomycosis. These observations are discussed in relation to the clinical features. Other unusual forms of oculomycosis are also discussed.
对91例确诊的眼真菌病连续病例进行了临床特征和流行病学参数研究。真菌性角膜溃疡为主要类型（76%），其次是眼内炎（20%）。曲霉菌是角膜真菌病的常见致病真菌（36%），其次是青霉菌属（29%）。镰刀菌角膜真菌病不像文献报道的那么常见。在眼内炎中，青霉菌作为致病真菌占优势。将这些病原体与健康对照的结膜菌群研究以及常见外伤物体的培养研究进行了比较。64%的病例在白内障手术后发生真菌性眼内炎。与预期相反，大多数病例的眼内炎在手术后2周内发作。有机物外伤是角膜真菌病的一个重要诱发因素。结合临床特征对这些观察结果进行了讨论。还讨论了其他不寻常的眼真菌病形式。
