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Commentary: The Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's Disease.

作者信息

Squitti Rosanna, Salustri Carlo, Rongioletti Mauro, Siotto Mariacristina

机构信息

Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli, Brescia, Italy.

Institute of Cognitive Sciences and Technologies (CNR), Rome, Italy.

出版信息

Front Neurol. 2017 Sep 25;8:503. doi: 10.3389/fneur.2017.00503. eCollection 2017.

DOI:10.3389/fneur.2017.00503
PMID:28993754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5622302/
Abstract
摘要

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本文引用的文献

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Characterization of plasma metal profiles in Alzheimer's disease using multivariate statistical analysis.使用多变量统计分析对阿尔茨海默病患者的血浆金属谱进行特征分析。
PLoS One. 2017 Jul 18;12(7):e0178271. doi: 10.1371/journal.pone.0178271. eCollection 2017.
2
Patients with Increased Non-Ceruloplasmin Copper Appear a Distinct Sub-Group of Alzheimer's Disease: A Neuroimaging Study.非铜蓝蛋白结合铜升高的患者似乎是阿尔茨海默病的一个独特亚组：一项神经影像学研究。
Curr Alzheimer Res. 2017;14(12):1318-1326. doi: 10.2174/1567205014666170623125156.
3
Multifactorial Analysis of a Biomarker Pool for Alzheimer Disease Risk in a North Indian Population.印度北部人群中阿尔茨海默病风险生物标志物池的多因素分析
Dement Geriatr Cogn Disord. 2017;44(1-2):25-34. doi: 10.1159/000477206. Epub 2017 Jun 21.
4
The Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's Disease.放弃阿尔茨海默病中铜离子治疗性螯合的理由。
Front Neurosci. 2017 Jun 2;11:317. doi: 10.3389/fnins.2017.00317. eCollection 2017.
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Oxidative Stress Markers and Metal Ions are Correlated With Cognitive Function in Alzheimer's Disease.氧化应激标志物和金属离子与阿尔茨海默病的认知功能相关。
Am J Alzheimers Dis Other Demen. 2017 Sep;32(6):353-359. doi: 10.1177/1533317517709549. Epub 2017 May 29.
6
The Relationship Between Copper, Iron, and Selenium Levels and Alzheimer Disease.铜、铁、硒水平与老年痴呆症的关系。
Biol Trace Elem Res. 2018 Feb;181(2):185-191. doi: 10.1007/s12011-017-1042-y. Epub 2017 May 13.
7
Modeling of the Pathogenic Effect of Copper Transporter Mutations That Cause Menkes and Wilson Diseases, Motor Neuropathy, and Susceptibility to Alzheimer's Disease.导致门克斯病和威尔逊病、运动神经病以及阿尔茨海默病易感性的铜转运蛋白突变的致病效应建模
J Biol Chem. 2017 Mar 10;292(10):4113-4122. doi: 10.1074/jbc.M116.756163. Epub 2017 Jan 24.
8
Measurements of serum non-ceruloplasmin copper by a direct fluorescent method specific to Cu(II).采用针对Cu(II)的直接荧光法测定血清非铜蓝蛋白铜。
Clin Chem Lab Med. 2017 Aug 28;55(9):1360-1367. doi: 10.1515/cclm-2016-0843.
9
Non-ceruloplasmin bound copper and ATP7B gene variants in Alzheimer's disease.阿尔茨海默病中与铜蓝蛋白无关的铜及ATP7B基因变体
Metallomics. 2016 Sep 1;8(9):863-73. doi: 10.1039/c6mt00101g. Epub 2016 Aug 8.
10
Non-Ceruloplasmin Copper Distinguishes A Distinct Subtype of Alzheimer's Disease: A Study of EEG-Derived Brain Activity.非铜蓝蛋白铜可区分阿尔茨海默病的一种独特亚型：一项基于脑电图衍生脑活动的研究
Curr Alzheimer Res. 2016;13(12):1374-1384. doi: 10.2174/1567205013666160603001131.