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胸椎复发性原发性骨血管外皮细胞瘤:一例报告并文献复习

Recurrent primary osseous hemangiopericytoma in the thoracic spine: a case report and literature review.

作者信息

Onoki Takahiro, Kanno Haruo, Aizawa Toshimi, Hashimoto Ko, Itoi Eiji, Ozawa Hiroshi

机构信息

Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.

Department of Orthopaedic Surgery, Tohoku Medical and Pharmaceutical University, 1-12-1, Fukumuro, Miyagino-ku, Sendai, 983-8512, Japan.

出版信息

Eur Spine J. 2018 Jul;27(Suppl 3):386-392. doi: 10.1007/s00586-017-5322-1. Epub 2017 Oct 9.

Abstract

PURPOSE

Primary osseous hemangiopericytoma (HPC) of the spine is exceedingly rare. HPC has malignant potential and has the capacity for metastasis and local recurrence. We herein present the first case of recurrent primary osseous HPC in the thoracic spine that was successfully treated by total spondylectomy at three vertebral levels and spinal reconstruction.

METHODS

We performed a two-stage operation for recurrent HPC using anterior and posterior approaches at the T5-T7 vertebrae. The preoperative embolization of the tumor was performed to prevent massive intraoperative bleeding. Then, total spondylectomy was performed (T5-T7) to resect the tumor. Anterior spinal reconstruction and posterior instrumentation were performed, with abundant bone autograft and allograft used to achieve sufficient boney fusion following the removal of the tumor.

RESULTS

At 2 years after surgery, the patient had made a sufficient recovery from his symptoms. The bone union was complete without tumor recurrence or implant failure.

CONCLUSIONS

Total spondylectomy and spinal reconstruction with instrumentation might be useful for performing the safe and adequate excision of recurrent HPC of the spine. However, patients should be closely monitored to detect local recurrence and the malignant degeneration of the tumor after surgery.

摘要

目的

脊柱原发性骨血管外皮细胞瘤(HPC)极为罕见。HPC具有恶性潜能,有转移和局部复发的能力。我们在此报告首例胸椎复发性原发性骨HPC,通过三个椎体节段的全脊椎切除术及脊柱重建成功治疗。

方法

我们采用前后联合入路,对T5 - T7椎体的复发性HPC进行两阶段手术。术前对肿瘤进行栓塞以防止术中大量出血。然后,进行全脊椎切除术(T5 - T7)以切除肿瘤。进行前路脊柱重建和后路内固定,在切除肿瘤后使用大量自体骨和异体骨移植以实现充分的骨融合。

结果

术后2年,患者症状恢复良好。骨愈合完全,无肿瘤复发或植入物失败。

结论

全脊椎切除术及器械辅助的脊柱重建对于安全、充分地切除脊柱复发性HPC可能是有用的。然而,术后应密切监测患者,以检测肿瘤的局部复发和恶性变。

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