Gligić A, Obradović M, Stojanović R, Hlaca D, Antonijević B, Arnautović A, Gaon J, Frusic M, Lee P, Goldgaber D
Institute of Immunology and Virology, Sarajevo, Yugoslavia.
Scand J Infect Dis. 1988;20(3):261-6. doi: 10.3109/00365548809032449.
Lung tissues from 547 rodents and 26 insectivores captured between 1981 and 1984 in central Bosnia (Fojnica) and central Serbia (Cacak), 2 regions known to be endemic for hemorrhagic fever with renal syndrome (HFRS), were examined for hantaviral antigen by the indirect immunofluorescent antibody technique. Antigen was detected in 17/231 Apodemus flavicollis, 3/187 A. sylvaticus, 1/46 A. agrarius, 4/32 Mus musculus, and 3/28 Clethrionomys glareolus. In addition, antibodies against Hantaan and Puumala viruses were found in serum pooled from 2 C. glareolus captured in Fojnica and 6 Pitimys subterraneus caught in Cacak. Sera of 27 HFRS patients from different parts of Yugoslavia were tested against 3 serotypes of hantavirus. Patients from Bosnia and Serbia had highest titers against Hantaan virus, while patients from Croatia had highest titers against Puumula virus, the agent of nephropathia epidemica.
1981年至1984年间，在波斯尼亚中部（福伊尼察）和塞尔维亚中部（查查克）这两个已知为肾综合征出血热（HFRS）流行地区捕获的547只啮齿动物和26只食虫动物的肺组织，采用间接免疫荧光抗体技术检测汉坦病毒抗原。在17只黄颈姬鼠、3只小林姬鼠、1只黑线姬鼠、4只小家鼠和3只棕背䶄中检测到抗原。此外，在福伊尼察捕获的2只棕背䶄和查查克捕获的6只地下鼹形田鼠的混合血清中发现了抗汉滩病毒和普马拉病毒的抗体。对来自南斯拉夫不同地区的27例HFRS患者的血清进行了3种血清型汉坦病毒检测。波斯尼亚和塞尔维亚的患者对汉滩病毒的滴度最高，而克罗地亚的患者对流行性肾病病原体普马拉病毒的滴度最高。
