Gligić A, Frusić M, Obradović M, Stojanović R, Hlaca D, Gibbs C J, Yanagihara R, Calisher C H, Gajdusek D C
Institute of Immunobiology and Virology, Belgrade, Yugoslavia.
Am J Trop Med Hyg. 1989 Jul;41(1):109-15.
Hantavirus antigens were detected in lung tissues of 8/113 Apodemus flavicollis and 2/17 Clethrionomys glareolus captured in 1984 in Fojnica, a region of Yugoslavia endemic for hemorrhagic fever with renal syndrome; hantavirus antigens were not detected in lung tissues from 126 other mammals collected in Fojnica. Three hantaviruses, 2 from A. flavicollis and 1 from C. glareolus, were isolated directly in Vero E6 cells and were partially characterized. The isolates from A. flavicollis, designated Fojnica virus, were antigenically similar but not identical to Hantaan virus strain 76-118, whereas the isolate from C. glareolus was antigenically indistinguishable from Puumala virus, strain Hällnäs B1. These data are consistent with previous studies that indicate the existence of at least 2 hantavirus serotypes in Yugoslavia.
1984年在南斯拉夫肾综合征出血热流行地区福伊尼察捕获的113只黄颈姬鼠中的8只以及17只棕背䶄中的2只的肺组织中检测到汉坦病毒抗原；在福伊尼察收集的其他126只哺乳动物的肺组织中未检测到汉坦病毒抗原。直接在非洲绿猴肾细胞（Vero E6）中分离出3株汉坦病毒，其中2株来自黄颈姬鼠，1株来自棕背䶄，并对其进行了部分特性鉴定。来自黄颈姬鼠的分离株，命名为福伊尼察病毒，其抗原性与汉滩病毒76-118株相似但不完全相同，而来自棕背䶄的分离株在抗原性上与普马拉病毒Hällnäs B1株无法区分。这些数据与之前表明南斯拉夫至少存在2种汉坦病毒血清型的研究结果一致。
