MacKenzie J, Belch J, Land D, Park R, McKillop J
General Medicine, Royal Infirmary, Glasgow.
Lancet. 1988 Sep 10;2(8611):592-5. doi: 10.1016/s0140-6736(88)90638-1.
The cause of chest pain in diffuse oesophageal spasm and "nutcracker" oesophagus is not clear. Spasm of the oesophageal muscle itself is probably not the cause, because pain and spasm are frequently not coincident. It is suggested instead that oesophageal ischaemia may be the cause of the pain, since the rewarming rate of the oesophagus after a standardised cold challenge was significantly longer in 9 patients with these motility disorders than in 21 normal controls. As rewarming time in other sites correlates with blood flow, these results are consistent with the hypothesis that the oesophagus is ischaemic in these patients.
弥漫性食管痉挛和“胡桃夹”食管中胸痛的病因尚不清楚。食管肌肉本身的痉挛可能不是病因，因为疼痛和痉挛常常并不同时出现。相反，有人提出食管缺血可能是疼痛的病因，因为在9例患有这些动力障碍的患者中，标准化冷刺激后食管的复温速率明显长于21名正常对照者。由于其他部位的复温时间与血流相关，这些结果与这些患者食管缺血的假说相符。
