Bamonte Giulio, Appeltans Andrea, Cicinelli Maria Vittoria, Querques Giuseppe
Department of Ophthalmology, University Hospital, Vrije Universiteit Brussel, Brussels, Belgium; and.
Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy.
Retin Cases Brief Rep. 2020 Winter;14(1):10-14. doi: 10.1097/ICB.0000000000000635.
To describe cases of reabsorption of subretinal acquired vitelliform material (acquired vitelliform lesion [AVL]) associated with vitreomacular disorders after 25-gauge pars plana vitrectomy and peeling of internal limiting membrane.
Data of consecutive patients who underwent 25-gauge transconjunctival pars plana vitrectomy for vitreomacular disorders at the Department of Ophthalmology of the University Hospital of Brussels (Belgium) were collected. Patients featuring AVL on fundus examination or on spectral domain optical coherence tomography were recruited. Patients were followed up for 12 months after surgery.
Four eyes of three consecutive white patients presenting AVL were included. Three cases were affected by macular pucker, whereas one case featured vitreomacular traction syndrome. Progressive flattening of the AVL after surgery was observed in three eyes of three patients. One eye did not show any resorption of the submacular accumulation. In two eyes, atrophy of the retinal pigment epithelium and the outer retinal layers was observed along with resolution of the AVL, with significant worsening of visual acuity postoperatively.
The outcome of surgery in cases of submacular AVL associated with vitreomacular interface syndromes could be heterogeneous and may depend on the duration of the disease and baseline optical coherence tomography characteristics of the lipofuscin accumulation.
描述25G经结膜平坦部玻璃体切除联合内界膜剥除术后,与玻璃体黄斑病变相关的视网膜下获得性卵黄样物质(获得性卵黄样病变[AVL])吸收的病例。
收集比利时布鲁塞尔大学医院眼科因玻璃体黄斑病变接受25G经结膜平坦部玻璃体切除术的连续患者的数据。招募眼底检查或光谱域光学相干断层扫描显示有AVL的患者。术后对患者进行12个月的随访。
纳入了3例连续出现AVL的白人患者的4只眼。3例为黄斑皱襞,1例为玻璃体黄斑牵引综合征。3例患者的3只眼中观察到术后AVL逐渐变平。1只眼黄斑下积液未出现任何吸收。2只眼中观察到视网膜色素上皮和视网膜外层萎缩,同时AVL消退,术后视力显著下降。
与玻璃体黄斑界面综合征相关的黄斑下AVL手术结果可能存在异质性,可能取决于疾病持续时间和脂褐素积聚的基线光学相干断层扫描特征。