• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大麻治疗阿片类药物流行时代的慢性疼痛:基于研讨会的社会医学科学综述。

Cannabis for the Treatment of Chronic Pain in the Era of an Opioid Epidemic: A Symposium-Based Review of Sociomedical Science.

机构信息

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Tufts University School of Dental Medicine, Boston, Massachusetts.

出版信息

Pain Med. 2019 Nov 1;20(11):2311-2323. doi: 10.1093/pm/pnx143.

DOI:10.1093/pm/pnx143
PMID:29016917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7963205/
Abstract

OBJECTIVE

This manuscript reviews medical literature published pertaining to the management of chronic pain with medical marijuana therapy (MMJ), with an emphasis on the social, medical, and legal aspects of therapy.

DESIGN

Narrative review of peer-reviewed literature.

METHODS

The 3rd Symposium on Controlled Substances and Their Alternatives for the Treatment of Pain was held in Boston on February 27, 2016, with a focus on MMJ for the treatment of chronic pain. Invited speakers had diverse backgrounds, including pain management, addiction psychiatry, neurology, and legal authorities. The purpose of this conference and this subsequent narrative review is to provide a medical, legal, and logistical framework for physicians and other health care providers to refer to when considering the initiation of medical marijuana therapy.

RESULTS

The invited speakers each covered a unique aspect of MMJ therapy for the treatment of chronic pain. These presentations highlighted the current data for and against the use of MMJ as a pain therapy. Optimal patient selection and screening, in addition to policy developments, were discussed.

CONCLUSIONS

Increasing interest in MMJ for chronic pain underscores a need for primary care and pain physicians to better understand the indications and evidence for its use free from cultural bias. Given a lack of full conclusive clinical utility, continued research is needed to better understand how to best utilize MMJ therapy for the treatment of chronic pain. Policy initiatives, such as enumerated indications, should follow medical science in order to prevent another abused substance epidemic.

摘要

目的

本文综述了与医用大麻疗法(MMJ)治疗慢性疼痛相关的医学文献,重点介绍了治疗的社会、医学和法律方面。

设计

同行评议文献的叙述性综述。

方法

2016 年 2 月 27 日在波士顿举行了第三届管制物质及其替代品治疗疼痛研讨会,重点是 MMJ 治疗慢性疼痛。受邀演讲者背景多样,包括疼痛管理、成瘾精神病学、神经病学和法律权威。本次会议和随后的叙述性综述旨在为医生和其他医疗保健提供者提供一个医学、法律和后勤框架,供他们在考虑启动医用大麻疗法时参考。

结果

受邀演讲者每人都涵盖了 MMJ 治疗慢性疼痛的独特方面。这些演讲强调了目前使用 MMJ 作为疼痛治疗的利弊数据。讨论了最佳患者选择和筛选,以及政策发展。

结论

对 MMJ 治疗慢性疼痛的兴趣增加,突出表明初级保健和疼痛医生需要更好地了解其使用的适应症和证据,避免文化偏见。鉴于缺乏完整的临床实用性,需要继续研究以更好地了解如何最好地利用 MMJ 治疗慢性疼痛。政策举措,如列举的适应症,应遵循医学科学,以防止另一种滥用物质的流行。

相似文献

1
Cannabis for the Treatment of Chronic Pain in the Era of an Opioid Epidemic: A Symposium-Based Review of Sociomedical Science.大麻治疗阿片类药物流行时代的慢性疼痛:基于研讨会的社会医学科学综述。
Pain Med. 2019 Nov 1;20(11):2311-2323. doi: 10.1093/pm/pnx143.
2
The Efficacy of Medical Marijuana in the Treatment of Cancer-Related Pain.医用大麻在治疗癌症相关疼痛方面的疗效。
J Palliat Med. 2020 Jun;23(6):809-816. doi: 10.1089/jpm.2019.0374. Epub 2020 Feb 26.
3
Pills to Pot: Observational Analyses of Cannabis Substitution Among Medical Cannabis Users With Chronic Pain.从药丸到大麻:慢性疼痛患者医用大麻使用者中大麻替代物的观察性分析。
J Pain. 2019 Jul;20(7):830-841. doi: 10.1016/j.jpain.2019.01.010. Epub 2019 Jan 26.
4
Frequency of cannabis and illicit opioid use among people who use drugs and report chronic pain: A longitudinal analysis.药物使用者中报告慢性疼痛的人与同时使用大麻和非法阿片类药物的频率:一项纵向分析。
PLoS Med. 2019 Nov 19;16(11):e1002967. doi: 10.1371/journal.pmed.1002967. eCollection 2019 Nov.
5
Cannabis Use is Associated with Lower Odds of Prescription Opioid Analgesic Use Among HIV-Infected Individuals with Chronic Pain.在患有慢性疼痛的艾滋病毒感染者中,使用大麻与使用处方阿片类镇痛药的几率较低有关。
Subst Use Misuse. 2018 Aug 24;53(10):1602-1607. doi: 10.1080/10826084.2017.1416408. Epub 2018 Jan 17.
6
Medical marijuana and pain management.医用大麻与疼痛管理。
Dis Mon. 2016 Sep;62(9):346-52. doi: 10.1016/j.disamonth.2016.05.014. Epub 2016 Jun 27.
7
Cannabis-based medicines for chronic neuropathic pain in adults.用于成人慢性神经性疼痛的大麻类药物。
Cochrane Database Syst Rev. 2018 Mar 7;3(3):CD012182. doi: 10.1002/14651858.CD012182.pub2.
8
Medical Cannabis Use Is Associated With Decreased Opiate Medication Use in a Retrospective Cross-Sectional Survey of Patients With Chronic Pain.在一项针对慢性疼痛患者的回顾性横断面调查中,医用大麻的使用与阿片类药物使用减少有关。
J Pain. 2016 Jun;17(6):739-44. doi: 10.1016/j.jpain.2016.03.002. Epub 2016 Mar 19.
9
Chronic Pain Clinical and Prescriptive Practices in the Cannabis Era.慢性疼痛的临床与大麻处方实践:大麻时代。
Pain Manag Nurs. 2022 Apr;23(2):109-121. doi: 10.1016/j.pmn.2021.11.009. Epub 2021 Dec 29.
10
Perspectives on cannabis as a substitute for opioid analgesics.关于大麻作为阿片类镇痛药替代品的观点。
Pain Manag. 2019 Mar 1;9(2):191-203. doi: 10.2217/pmt-2018-0051. Epub 2019 Jan 25.

引用本文的文献

1
The endocannabinoid system and breathing.内源性大麻素系统与呼吸。
Front Neurosci. 2023 Apr 18;17:1126004. doi: 10.3389/fnins.2023.1126004. eCollection 2023.
2
Analyzing the Perspectives of Health Professionals and Legal Cannabis Users on the Treatment of Chronic Pain With Cannabidiol: Protocol for a Scoping Review.分析健康专业人员和合法大麻使用者对大麻二酚治疗慢性疼痛的看法:一项范围综述方案
JMIR Res Protoc. 2023 Jan 20;12:e37697. doi: 10.2196/37697.
3
Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process.医用大麻治疗慢性疼痛的剂量和给药共识建议:改良德尔菲法的结果
J Cannabis Res. 2021 Jul 2;3(1):22. doi: 10.1186/s42238-021-00073-1.
4
Cannabis for Chronic Pain: Not Ready for Prime Time.大麻用于慢性疼痛:尚不适用于主流治疗。
Am J Public Health. 2019 Jan;109(1):50-51. doi: 10.2105/AJPH.2018.304593.
5
Is There Less Opioid Abuse in States Where Marijuana Has Been Decriminalized, Either for Medicinal or Recreational Use? A Clin-IQ.在大麻已合法化用于医疗或娱乐用途的州,阿片类药物滥用情况是否较少?一项临床智能研究。
J Patient Cent Res Rev. 2019 Oct 28;6(4):267-273. doi: 10.17294/2330-0698.1704. eCollection 2019 Fall.
6
Patients' and clinicians' perspectives of co-use of cannabis and opioids for chronic non-cancer pain management in primary care.患者和临床医生对在初级保健中同时使用大麻和阿片类药物治疗慢性非癌症疼痛的看法。
Int J Drug Policy. 2019 Jan;63:23-28. doi: 10.1016/j.drugpo.2018.09.002. Epub 2018 Nov 23.
7
Emerging Evidence for Cannabis' Role in Opioid Use Disorder.大麻在阿片类物质使用障碍中作用的新证据。
Cannabis Cannabinoid Res. 2018 Sep 1;3(1):179-189. doi: 10.1089/can.2018.0022. eCollection 2018.

本文引用的文献

1
State Medical Marijuana Laws and the Prevalence of Opioids Detected Among Fatally Injured Drivers.州医用大麻法律与在致命伤驾驶员中检测到的阿片类药物流行情况。
Am J Public Health. 2016 Nov;106(11):2032-2037. doi: 10.2105/AJPH.2016.303426. Epub 2016 Sep 15.
2
Medication use and the risk of motor vehicle collisions among licensed drivers: A systematic review.持证驾驶员的药物使用与机动车碰撞风险:一项系统综述。
Accid Anal Prev. 2016 Nov;96:255-270. doi: 10.1016/j.aap.2016.08.001. Epub 2016 Aug 29.
3
Factors associated with having a medical marijuana card among Veterans with recent substance use in VA outpatient treatment.在退伍军人事务部(VA)门诊治疗中近期有药物使用情况的退伍军人中,与持有医用大麻卡相关的因素。
Addict Behav. 2016 Dec;63:132-6. doi: 10.1016/j.addbeh.2016.07.006. Epub 2016 Jul 8.
4
Anxiety, depression and risk of cannabis use: Examining the internalising pathway to use among Chilean adolescents.焦虑、抑郁与大麻使用风险:探究智利青少年使用大麻的内化途径。
Drug Alcohol Depend. 2016 Sep 1;166:109-15. doi: 10.1016/j.drugalcdep.2016.06.032. Epub 2016 Jul 1.
5
Medical Board Expectations for Physicians Recommending Marijuana.医学委员会对推荐大麻的医生的期望。
JAMA. 2016 Aug 9;316(6):577-8. doi: 10.1001/jama.2016.7741.
6
Changes in Cannabis Potency Over the Last 2 Decades (1995-2014): Analysis of Current Data in the United States.过去20年(1995 - 2014年)大麻效力的变化:美国当前数据分析
Biol Psychiatry. 2016 Apr 1;79(7):613-9. doi: 10.1016/j.biopsych.2016.01.004. Epub 2016 Jan 19.
7
Prevalence of marijuana use does not differentially increase among youth after states pass medical marijuana laws: Commentary on and reanalysis of US National Survey on Drug Use in Households data 2002-2011.在各州通过医用大麻法律后,青少年中使用大麻的流行率并未出现差异增长:对2002 - 2011年美国全国药物使用家庭调查数据的评论与重新分析
Int J Drug Policy. 2016 Mar;29:9-13. doi: 10.1016/j.drugpo.2016.01.015. Epub 2016 Feb 1.
8
Efficacy, tolerability and safety of cannabinoids in chronic pain associated with rheumatic diseases (fibromyalgia syndrome, back pain, osteoarthritis, rheumatoid arthritis): A systematic review of randomized controlled trials.大麻素类药物治疗风湿性疾病相关慢性疼痛(纤维肌痛综合征、背痛、骨关节炎、类风湿关节炎)的疗效、耐受性及安全性:随机对照试验的系统评价
Schmerz. 2016 Feb;30(1):47-61. doi: 10.1007/s00482-015-0084-3.
9
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial.大麻二酚治疗耐药性癫痫患者:一项开放标签的干预性试验。
Lancet Neurol. 2016 Mar;15(3):270-8. doi: 10.1016/S1474-4422(15)00379-8. Epub 2015 Dec 24.
10
Cannabis for the Management of Pain: Assessment of Safety Study (COMPASS).大麻用于疼痛管理:安全性研究评估(COMPASS)。
J Pain. 2015 Dec;16(12):1233-1242. doi: 10.1016/j.jpain.2015.07.014. Epub 2015 Sep 16.