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孤立性肺动静脉畸形导致的中风

Stroke resulting from an isolated pulmonary arteriovenous malformation.

作者信息

Saidman Jakob, Abdou Hossam, Sampath Kumar Sridhar

机构信息

North Campus, Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania, USA.

Department of Cardiology, Regional Hospital of Scranton, Scranton, Pennsylvania, USA.

出版信息

BMJ Case Rep. 2017 Oct 10;2017:bcr-2017-221000. doi: 10.1136/bcr-2017-221000.

Abstract

Isolated pulmonary arteriovenous malformations (PAVM) are rare, but can be responsible for paradoxical embolic events. It is important to recognise these situations early and intervene quickly to attain the best outcome. We describe the case of a 45-year-old woman with a long-standing history of migraines with aura who presented to the emergency department with left-sided weakness and slurred speech. Work-up was unclear and she was diagnosed with cryptogenic stroke. Follow-up transoesophageal echocardiogram was suggestive of an atrial septal defect, though no clear defect was evident. Pulmonary angiography revealed an isolated PAVM arising from the right lower lung segmental artery with a 2 mm feeding artery leading into 3-4 mm of dysplastic vessel that connects to the vein. The vessel was embolised successfully using a combination of a 4 mm Amplatzer Vascular Plug in the distal feeding artery and a 4 mm Nester coil proximally.

摘要

孤立性肺动静脉畸形(PAVM)较为罕见,但可导致反常栓塞事件。早期识别这些情况并迅速干预以获得最佳结果非常重要。我们描述了一名45岁女性的病例,她有长期的偏头痛伴先兆病史,因左侧肢体无力和言语含糊不清就诊于急诊科。检查结果不明确,她被诊断为隐源性卒中。后续经食管超声心动图提示存在房间隔缺损,但未发现明确缺损。肺血管造影显示一个孤立性PAVM,起源于右下肺段动脉,有一条2毫米的供血动脉通向3 - 4毫米发育异常的血管,该血管与静脉相连。使用一个4毫米的Amplatzer血管封堵器封堵远端供血动脉,并在近端使用一个4毫米的Nester弹簧圈,成功栓塞了该血管。

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本文引用的文献

1
Implications of an Incidental Pulmonary Arteriovenous Malformation.偶发性肺动静脉畸形的影响
J Investig Med High Impact Case Rep. 2016 Mar 8;4(1):2324709616637190. doi: 10.1177/2324709616637190. eCollection 2016 Jan-Mar.
2
Isolated asymptomatic pulmonary arteriovenous malformation presenting with ischaemic stroke.
J Clin Neurosci. 2016 Jul;29:189-91. doi: 10.1016/j.jocn.2016.01.006. Epub 2016 Feb 17.
3
Strokes in young adults: epidemiology and prevention.年轻成年人中的中风:流行病学与预防
Vasc Health Risk Manag. 2015 Feb 24;11:157-64. doi: 10.2147/VHRM.S53203. eCollection 2015.
4
Pulmonary arteriovenous malformations.肺动静脉畸形
Am J Respir Crit Care Med. 2014 Dec 1;190(11):1217-28. doi: 10.1164/rccm.201407-1254CI.

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