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评估反馈模块在香港模拟 EQ-5D-5L 健康状态值的应用。

Assessing the Use of a Feedback Module to Model EQ-5D-5L Health States Values in Hong Kong.

机构信息

The JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

The EuroQol Research Foundation, Rotterdam, The Netherlands.

出版信息

Patient. 2018 Apr;11(2):235-247. doi: 10.1007/s40271-017-0278-0.

Abstract

BACKGROUND

An international valuation protocol exists for obtaining societal values for each of the 3125 health states of the five-level EuroQol-five dimensions (EQ-5D-5L) questionnaire. A feedback module (FM) that can be related to theoretical models used in behavioral economics was recently included in this protocol.

OBJECTIVES

Our objective was to assess the impact of using an FM to estimate an EQ-5D-5L value set in Hong Kong.

METHODS

EQ-5D-5L health states were elicited using a composite time trade-off (C-TTO) and a discrete-choice (DC) experiment. Use of the FM according to participant characteristics and the impact of the FM on the number of inconsistent C-TTO responses were assessed. We employed a main-effects hybrid model that combined data from both elicitation techniques.

RESULTS

In total, 1014 individuals completed the survey. The sample was representative of the general Chinese Hong Kong population in terms of sex, educational attainment, marital status, and most age groups but not for employment status. The use of the FM reduced the number of C-TTO inconsistencies. Participant characteristics differed significantly between those who used and did not use the FM. The model without a constant resulted in logical consistent coefficients and was therefore selected as the model to produce the value set. The predicted EQ-5D-5L values ranged from -0.864 to 1.

CONCLUSIONS

The use of an FM to allow participants to exclude C-TTO responses reduced the number of inconsistent responses and improved the quality of the data when estimating an EQ-5D-5L value set in Hong Kong.

摘要

背景

为获取 EQ-5D-5L 问卷的 3125 个健康状态的每个状态的社会价值,存在一个国际评估方案。最近,该方案纳入了一个反馈模块(FM),该模块可与行为经济学中使用的理论模型相关联。

目的

我们的目的是评估在香港使用 FM 来评估 EQ-5D-5L 值集的影响。

方法

使用复合时间权衡(C-TTO)和离散选择(DC)实验来引出 EQ-5D-5L 健康状态。根据参与者特征使用 FM 以及 FM 对不一致 C-TTO 反应数量的影响进行了评估。我们采用了一种主效应混合模型,该模型结合了两种 elicitation 技术的数据。

结果

共有 1014 人完成了调查。该样本在性别、教育程度、婚姻状况和大多数年龄组方面与一般中国香港人口具有代表性,但在就业状况方面没有代表性。使用 FM 减少了 C-TTO 不一致的数量。使用和不使用 FM 的参与者特征存在显著差异。没有常数的模型产生了逻辑一致的系数,因此被选为产生值集的模型。预测的 EQ-5D-5L 值范围从-0.864 到 1。

结论

在香港评估 EQ-5D-5L 值集时,使用 FM 允许参与者排除 C-TTO 响应,减少了不一致响应的数量,并提高了数据的质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59bc/5845074/f569ba2a7251/40271_2017_278_Fig1_HTML.jpg

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