Liu Wenting, Ma Tiantian, Zhou Chunju, Zang Xiao, Li Langjin, Zhang Baojun, Du Wei, Zhang Weili, Chen Kunming
College of Life Sciences, Northwest A&F University, Yangling 712100, Shaanxi, China.
Sheng Wu Gong Cheng Xue Bao. 2016 May 25;32(5):541-553. doi: 10.13345/j.cjb.150351.
Transcription factor is a key trans-acting factor to mediate stress response by regulating gene expression. Plants have developed a series of mechanisms to modulate development, stress response, signaling and disease resistance at transcription level. DNA binding with one finger (DOF), containing one C₂-C₂ zinc finger domain, is a special plant transcription factor. Specifically, the conserved domain at N-terminus of DOF has multiple functions, including interacting with DNA and protein, which could be involved in plant development and stress response. Although many DOF family genes are characterized in plant stress response, it is not clear if DOF genes have functions in cereal plants. In the present paper, the role of DOF family genes on cereal plants were discussed based on a comprehensive phylogenetic relationship analysis, expression profiles in different tissues and various environmental conditions. The results obtained here will provide an important reference for further understanding the mechanism of gramineous crops in stress resistance.
转录因子是通过调控基因表达来介导应激反应的关键反式作用因子。植物已经进化出一系列机制，在转录水平上调节发育、应激反应、信号传导和抗病性。单指DNA结合蛋白（DOF）含有一个C₂-C₂锌指结构域，是一种特殊的植物转录因子。具体而言，DOF蛋白N端的保守结构域具有多种功能，包括与DNA和蛋白质相互作用，这可能参与植物的发育和应激反应。尽管许多DOF家族基因在植物应激反应中已有特征描述，但尚不清楚DOF基因在谷类植物中是否具有功能。本文基于全面的系统发育关系分析、不同组织和各种环境条件下的表达谱，探讨了DOF家族基因在谷类植物中的作用。本文获得的结果将为进一步了解禾本科作物的抗逆机制提供重要参考。
