甲状腺髓样癌：利用I-131间碘苄胍对纵隔转移灶进行定位

Medullary thyroid carcinoma: localization of a mediastinal metastasis with I-131 MIBG.

作者信息

Laflamme L, Taillefer R, Duranceau A, Verdy M, Schürch W

机构信息

Department of Nuclear Medicine, Hôtel-Dieu de Montréal, University of Montréal, Canada.

出版信息

Clin Nucl Med. 1988 Aug;13(8):577-9.

PMID:2901928

Abstract

An I-131 metaiodobenzylguanidine (MIBG) scan was performed in a patient with a familial history of multiple endocrine neoplasia (MEN) type 2 and recurrent medullary thyroid carcinoma (MTC). The scan revealed a mediastinal metastasis from her MTC and there was also an imaging pattern of bilateral adreno-medullary hyperplasia. Although the literature indicates that I-131-MIBG scanning is not sufficiently sensitive for the detection of MTC, this procedure has proven to be of value in the management of chosen patients with MEN-associated MTC.

摘要

对一名有2型多发性内分泌腺瘤病（MEN）家族史及复发性甲状腺髓样癌（MTC）的患者进行了碘-131间碘苄胍（MIBG）扫描。扫描显示其MTC出现纵隔转移，并且还有双侧肾上腺髓质增生的影像学表现。尽管文献表明碘-131-MIBG扫描对MTC的检测灵敏度不足，但该检查已被证明对选定的MEN相关MTC患者的管理具有价值。