Department of Psychiatry and Medical Psychology, Medical University of Plovdiv, Plovdiv, Bulgaria.
Research Complex for Translational Neuroscience, Medical University of Plovdiv, Plovdiv, Bulgaria.
Balkan Med J. 2017 Dec 1;34(6):493-503. doi: 10.4274/balkanmedj.2017.1160. Epub 2017 Oct 11.
Translation as a notion and procedure is deeply embodied in medical science and education. Translation includes the possibility to translate data across disciplines to improve diagnosis and treatment procedures. The evidence accumulated using translation serves as a vehicle for reification of medical diagnoses. There are promising, established post hoc correlations between the different types of clinical tools (interviews and inventories) and neuroscience. The various measures represent statistical correlations that must now be integrated into diagnostic standards and procedures but this, as a whole, is a step forward towards a better understanding of the mechanisms underlying psychopathology in general and depression in particular. Here, we focus on functional magnetic resonance imaging studies using a trans-disciplinary approach and attempt to establish bridges between the different fields. We will selectively highlight research areas such as imaging genetics, imaging immunology and multimodal imaging, as related to the diagnosis and management of depression.
翻译作为一种概念和过程，深深地体现在医学科学和教育中。翻译包括跨学科翻译数据的可能性，以改善诊断和治疗程序。使用翻译积累的证据是医学诊断具体化的工具。不同类型的临床工具（访谈和清单）和神经科学之间存在有希望的、已确立的事后相关性。各种措施代表了必须纳入诊断标准和程序的统计相关性，但这总体上是朝着更好地理解精神病理学一般和特别是抑郁症的潜在机制迈出的一步。在这里，我们专注于使用跨学科方法进行功能磁共振成像研究，并试图在不同领域之间建立桥梁。我们将有选择地突出成像遗传学、成像免疫学和多模态成像等研究领域，因为它们与抑郁症的诊断和治疗有关。
