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荧光化学传感器:过去、现在和未来。

Fluorescent chemosensors: the past, present and future.

机构信息

Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.

Department of Chemistry, University of Bath, Bath, BA2 7AY, UK.

出版信息

Chem Soc Rev. 2017 Dec 7;46(23):7105-7123. doi: 10.1039/c7cs00240h. Epub 2017 Oct 11.

DOI:10.1039/c7cs00240h
PMID:29019488
Abstract

Fluorescent chemosensors for ions and neutral analytes have been widely applied in many diverse fields such as biology, physiology, pharmacology, and environmental sciences. The field of fluorescent chemosensors has been in existence for about 150 years. In this time, a large range of fluorescent chemosensors have been established for the detection of biologically and/or environmentally important species. Despite the progress made in this field, several problems and challenges still exist. This tutorial review introduces the history and provides a general overview of the development in the research of fluorescent sensors, often referred to as chemosensors. This will be achieved by highlighting some pioneering and representative works from about 40 groups in the world that have made substantial contributions to this field. The basic principles involved in the design of chemosensors for specific analytes, problems and challenges in the field as well as possible future research directions are covered. The application of chemosensors in various established and emerging biotechnologies, is very bright.

摘要

荧光化学传感器在离子和中性分析物的检测方面有着广泛的应用,涉及生物学、生理学、药理学和环境科学等多个领域。荧光化学传感器领域已经存在了大约 150 年。在这段时间里,已经建立了大量的荧光化学传感器来检测具有生物学和/或环境重要性的物种。尽管在这一领域取得了进展,但仍存在一些问题和挑战。本教程综述介绍了荧光传感器(通常称为化学传感器)研究的历史和发展概况。这将通过突出来自全球约 40 个组的一些开创性和代表性工作来实现,这些工作为该领域做出了重大贡献。涵盖了设计针对特定分析物的化学传感器所涉及的基本原理、该领域的问题和挑战以及可能的未来研究方向。化学传感器在各种已建立和新兴生物技术中的应用前景非常广阔。

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