Angiotensin-converting enzyme activity in experimental alcoholic fatty liver of the rat. - Suppr | 超能文献

Angiotensin-converting enzyme activity in experimental alcoholic fatty liver of the rat.

作者信息

Antoniello S, Auletta M, Vatiero V, Nigro C, Cacciatore L

机构信息

Department of Internal Medicine, 2nd School of Medicine, University of Naples, Italy.

出版信息

Enzyme. 1988;40(1):14-7. doi: 10.1159/000469135.

DOI:10.1159/000469135

Abstract

Angiotensin-converting enzyme (ACE) activity was found increased in serum of patients with chronic alcoholism. We studied this enzymatic activity in serum and liver tissue of rats with alcoholic fatty liver due to prolonged intake of ethanol with a liquid diet, according to De Carli and Lieber. Serum and liver ACE activity did not show any significant increase in rats with alcoholic fatty liver when compared with controls, whereas gamma-glutamyltransferase activity exhibited a striking enhancement in serum and liver. Our data suggest that ACE is not an alcohol-induced enzyme in the experimental rat model.

摘要

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