Freitas Ruffo de, Nunes Rodrigo Disconzi, Martins Edesio, Curado Maria Paula, Freitas Nilceana Maya Aires, Soares Leonardo Ribeiro, Oliveira José Carlos
- Federal University of Goiás (HC/UFG), Mastology Program, Clinics Hospital, Goiânia, GO, Brazil.
- Goiás Association to Cancer Combat (ACCG), Araújo Jorge Hospital, Goiânia, GO, Brazil.
Rev Col Bras Cir. 2017 Sep-Oct;44(5):435-443. doi: 10.1590/0100-69912017005003.
to analyze the overall survival and prognostic factors of women with breast cancer in the city of Goiânia.
this is a retrospective, cross-sectional, observational study that included women with malignant neoplasms of the breast identified by the Goiânia Population-based Cancer Registry. The variables studied were age at diagnosis, tumor size, staging, axillary lymph node involvement, tumor grade, disease extent, hormone receptors, and c-erb-B2 oncoprotein. We performed overall survival analyzes of five and ten years.
we included 2,273 patients in the study, with an overall survival of 72.1% in five years and 57.8% in ten years. In the multivariate analysis adjusted for tumor size, the factors that influenced the prognosis were axillary lymph nodes, histological grade, progesterone receptor, c erb B2, T staging and disease extension.
overall survival in ten years is below that observed in other countries, and possibly reflects what happens with the majority of the Brazilian population. The prognostic factors found in this population follow the same international patterns.
分析戈亚尼亚市乳腺癌女性患者的总生存率及预后因素。
这是一项回顾性、横断面观察性研究，纳入了戈亚尼亚市基于人群的癌症登记处确诊的乳腺恶性肿瘤女性患者。研究的变量包括诊断时的年龄、肿瘤大小、分期、腋窝淋巴结受累情况、肿瘤分级、疾病范围、激素受体以及c-erb-B2癌蛋白。我们进行了5年和10年的总生存分析。
本研究纳入2273例患者，5年总生存率为72.1%，10年总生存率为57.8%。在针对肿瘤大小进行校正的多因素分析中，影响预后的因素包括腋窝淋巴结、组织学分级、孕激素受体、c-erb B2、T分期和疾病范围。
10年总生存率低于其他国家观察到的情况，可能反映了巴西大多数人群的情况。该人群中发现的预后因素遵循相同的国际模式。
