Oliveira Jânia Cristiane de Souza, Galvão Noemi Dreyer, Andrade Amanda Cristina de Souza, Silva Ageo Mário Cândido da
Universidade Federal de Rondonópolis, School of Health Sciences - Rondonópolis, (MT), Brazil.
Universidade Federal de Mato Grosso, Institute of Public Health - Cuiabá (MT), Brazil.
Rev Bras Epidemiol. 2025 Mar 3;28:e250010. doi: 10.1590/1980-549720250010. eCollection 2025.
To analyze the overall and cancer-specific five-year survival rates for female breast cancer in Greater Cuiabá, Mato Grosso, Brazil.
A non-concurrent, population-based cohort study using the Population-Based Cancer Registry of Greater Cuiabá (Cuiabá and Varzea Grande), including women diagnosed with breast cancer from 2008 to 2013, followed through 2018 in the regional mortality database. The sample consisted of a total of 1,220 women. Five-year survival analysis was performed using Kaplan-Meier curves and the Cox proportional hazards regression model, computing hazard ratios for variable estimation. Survival curves were compared using the log-rank test (p<0.05). Probabilistic linkage technique by the RecLink III software and survival analysis were conducted using STATA software version 12.0.
There was no statistical difference between the overall (OS) and cancer-specific survival (SS) rates (OS 78.0%, 95%CI 75.6-80.2; SS 81.0%, 95%CI 78.7-83.2). Women with lower educational levels (OS=58.33%; SS=64.89%) and those without a partner (OS 64.81%; SS 70.41%) exhibited poorer survival.
This study demonstrates that educational level and marital status significantly impact both overall and cancer-specific survival rates for female breast cancer. There is a need to propose policies that address the profile of women with lower survival rates.
分析巴西马托格罗索州大库亚巴市女性乳腺癌的总体和癌症特异性五年生存率。
采用基于人群的非同期队列研究，利用大库亚巴市（库亚巴和瓦尔泽亚格兰德）的基于人群的癌症登记处的数据，纳入2008年至2013年被诊断为乳腺癌的女性，并在区域死亡率数据库中随访至2018年。样本共包括1220名女性。使用Kaplan-Meier曲线和Cox比例风险回归模型进行五年生存分析，计算变量估计的风险比。使用对数秩检验比较生存曲线（p<0.05）。通过RecLink III软件进行概率链接技术，并使用STATA软件12.0版本进行生存分析。
总体生存率（OS）和癌症特异性生存率（SS）之间无统计学差异（OS 78.0%，95%CI 75.6-80.2；SS 81.0%，95%CI 78.7-83.2）。教育水平较低的女性（OS=58.33%；SS=64.89%）和没有伴侣的女性（OS 64.81%；SS 70.41%）生存率较差。
本研究表明，教育水平和婚姻状况对女性乳腺癌的总体和癌症特异性生存率均有显著影响。有必要提出针对生存率较低女性特征的政策。
