Nunes Rodrigo Disconzi, Martins Edesio, Freitas-Junior Ruffo, Curado Maria Paula, Freitas Nilceana Maya Aires, Oliveira José Carlos de
Postgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Goiás, Brazil.
Rev Col Bras Cir. 2011 Jul-Aug;38(4):212-6. doi: 10.1590/s0100-69912011000400002.
To describe cases of breast cancer in women living in Goiânia from 1989-2003.
We conducted a retrospective, descriptive stud, which included all cases of breast cancer occurring in residents of Goiânia, identified by the Population-Based Cancer Registry of Goiânia (RCBPGO) in the period from 1989 to 2003. The variables were: age, method of diagnosis, topographic location, morphology and extent of breast cancer. We used frequencies and percentage rates, and Poisson regression to determine the annual percentage change (APC).
We identified 3204 cases of breast cancer. The most frequent topographic location was the superior-lateral quadrant (53.7%). Infiltrating ductal carcinoma (IDC) was the most frequent, with 2582 cases (80.6%), followed by infiltrating lobular carcinoma (ILC), with 155 cases (4.8%). There was a significant increase of both the IDC and the ILC, with APCs of 11.0% and 15.4%, respectively. The ratio between IDC and ILC was not influenced by age (p = 0.98). As for tumor extent at diagnosis, 45.6% were located in the breast, and the APC was 16.1% (CI = 12.4 to 20.0, p <0.001). There was a trend of APC reduction of metastatic cases (-3.8, CI = -8.6 to 1.2, p = 0.12).
The topographical location and histological type of breast cancer in the city of Goiania followed the pattern of other countries. The main morphological types were not influenced by age. There was a large increase in initial cases.
描述1989年至2003年居住在戈亚尼亚的女性乳腺癌病例情况。
我们开展了一项回顾性描述性研究，纳入了1989年至2003年期间戈亚尼亚基于人群的癌症登记处（RCBPGO）确定的戈亚尼亚居民中发生的所有乳腺癌病例。变量包括：年龄、诊断方法、肿瘤部位、形态学以及乳腺癌的范围。我们使用了频率和百分比率，并采用泊松回归来确定年度百分比变化（APC）。
我们共识别出3204例乳腺癌病例。最常见的肿瘤部位是外上象限（53.7%）。浸润性导管癌（IDC）最为常见，有2582例（80.6%），其次是浸润性小叶癌（ILC），有155例（4.8%）。IDC和ILC均显著增加，APC分别为11.0%和15.4%。IDC与ILC的比例不受年龄影响（p = 0.98）。至于诊断时的肿瘤范围，45.6%位于乳腺内，APC为16.1%（CI = 12.4至20.0，p <0.001）。转移病例的APC有下降趋势（-3.8，CI = -8.6至1.2，p = 0.12）。
戈亚尼亚市乳腺癌的肿瘤部位和组织学类型遵循其他国家的模式。主要形态学类型不受年龄影响。初发病例大幅增加。
