Vaena Michel Luciano Holger Toledano, Sinnecker João Paulo, Pinto Bruno Benedetti, Neves Mario Fritsch Toros, Serra-Guimarães Fernando, Marques Ruy Garcia
- University of the State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
- Brazilian Center for Physical Research, Department of Experimental Physics of Low Energies, Rio de Janeiro, RJ, Brazil.
Rev Col Bras Cir. 2017 Sep-Oct;44(5):498-504. doi: 10.1590/0100-69912017005012.
to evaluate the effects of increasing pressures on the cutaneous blood flow in the skin of pigs.
we conducted an experimental study in pigs submitted to subcutaneous magnetic implants (n=30). After healing, were applied external magnets with varying magnetic forces to the skin, generating compression. We evaluated the cutaneous circulation of the skin under compression by the Laser Speckle Contrast Imaging (LSCI) technique. We measured the depth of the implants by ultrasonography, and applied computational simulations to the calculation of the different pressure values, considering the different distances between implants and external magnets.
nineteen implants presented complications. The remaining 11 were submitted to different magnetic compression forces and perfusion analysis. Two linear regression models showed an inverse correlation between exerted pressure and cutaneous perfusion, with significant variation, mainly in the initial pressure increases, of up to 20mmHg.
The main reduction in cutaneous blood flow resulted from initial increases of up to 20 mmHg. The results suggest that tissue ischemia can occur even in low-pressure regimes, which could contribute to the appearance of skin lesions, particularly ulcers related to medical devices.
评估压力增加对猪皮肤血流量的影响。
我们对30头植入皮下磁性植入物的猪进行了一项实验研究。愈合后，将具有不同磁力的外部磁体应用于皮肤，产生压迫。我们通过激光散斑对比成像（LSCI）技术评估受压皮肤的皮肤循环。我们通过超声检查测量植入物的深度，并考虑植入物与外部磁体之间的不同距离，应用计算模拟来计算不同的压力值。
19个植入物出现并发症。其余11个接受了不同的磁压力和灌注分析。两个线性回归模型显示施加的压力与皮肤灌注之间呈负相关，变化显著，主要在初始压力增加高达20mmHg时。
皮肤血流量的主要减少是由初始增加高达20mmHg引起的。结果表明，即使在低压状态下也可能发生组织缺血，这可能导致皮肤病变的出现，特别是与医疗器械相关的溃疡。
