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Linking the sympathetic nervous system to the inflammasome: towards new therapeutics for atherosclerotic cardiovascular disease.

作者信息

Karakas Mahir, Haase Tina, Zeller Tanja

机构信息

Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.

German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel, Germany.

出版信息

Eur Heart J. 2018 Jan 1;39(1):70-72. doi: 10.1093/eurheartj/ehx374.

DOI:10.1093/eurheartj/ehx374
PMID:29020243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5837356/
Abstract
摘要

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本文引用的文献

1
IL-18 cleavage triggers cardiac inflammation and fibrosis upon β-adrenergic insult.白细胞介素-18 的切割在β-肾上腺素刺激下引发心脏炎症和纤维化。
Eur Heart J. 2018 Jan 1;39(1):60-69. doi: 10.1093/eurheartj/ehx261.
2
Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial.洛马司他莫在急性心肌梗死后住院患者中的心血管结局影响：一项随机临床试验。
JAMA. 2016 Apr 19;315(15):1591-9. doi: 10.1001/jama.2016.3609.
3
A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus.一项关于抗白细胞介素-18单克隆抗体治疗2型糖尿病疗效和安全性的研究。
PLoS One. 2016 Mar 1;11(3):e0150018. doi: 10.1371/journal.pone.0150018. eCollection 2016.
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Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial.急性冠脉综合征后达拉帕利德对主要冠脉事件的影响：SOLID-TIMI 52 随机临床试验。
JAMA. 2014 Sep 10;312(10):1006-15. doi: 10.1001/jama.2014.11061.
5
Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure.白细胞介素-18作为急性心肌梗死和心力衰竭的治疗靶点。
Mol Med. 2014 Jun 12;20(1):221-9. doi: 10.2119/molmed.2014.00034.
6
Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial.维拉唑布丁与急性冠状动脉综合征患者心血管事件：VISTA-16 随机临床试验。
JAMA. 2014 Jan 15;311(3):252-62. doi: 10.1001/jama.2013.282836.
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Moving beyond JUPITER: will inhibiting inflammation reduce vascular event rates?超越 JUPITER：抑制炎症能否降低血管事件发生率？
Curr Atheroscler Rep. 2013 Jan;15(1):295. doi: 10.1007/s11883-012-0295-3.
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Inflammation in atherosclerosis.动脉粥样硬化中的炎症。
Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2045-51. doi: 10.1161/ATVBAHA.108.179705.
9
Inflammasome: NAIPs: pathogen-sensing proteins.炎性小体：NAIPs：病原体感知蛋白。
Nat Rev Immunol. 2011 Sep 9;11(10):644. doi: 10.1038/nri3069.
10
Beta-adrenergic stimulation and myocardial function in the failing heart.β肾上腺素能刺激与衰竭心脏的心肌功能。
Heart Fail Rev. 2009 Dec;14(4):225-41. doi: 10.1007/s10741-008-9132-8.