泰国人群中 Behçet 葡萄膜炎的眼部表现和视觉结果。
Ocular Manifestations and Visual Outcomes of Behçet's Uveitis in a Thai population.
机构信息
a Department of Ophthalmology, Faculty of Medicine , Chiang Mai University , Thailand.
b Department of Ophthalmology , Erasmus Medical Centre , Rotterdam , The Netherlands.
出版信息
Ocul Immunol Inflamm. 2019;27(1):2-6. doi: 10.1080/09273948.2017.1351570. Epub 2017 Oct 11.
PURPOSE
To report on ocular manifestations and visual outcomes of Thai patients with Behçet's Uveitis (BU).
METHODS
We reviewed medical records of 50 BU patients (31 males and 19 females). Ocular manifestations, treatment modalities, complications, and visual outcomes were registered.
RESULTS
Ocular involvement was bilateral in 76% of patients, resulting in 89 affected eyes. Panuveitis and posterior uveitis were the most common types. Retinal vasculitis was noted in majority of affected eyes and specifically arteritis was noticed in 32/57(56%). Most patients received combination therapy of systemic corticosteroids and immunosuppressive agents (azathioprine 72%). At final visit, VA ≤20/200 was observed in 25 affected eyes (28%). Risk factors for poor visual outcome were poor visual acuity at presentation (p < 0.001) and development of optic atrophy (p = 0.01).
CONCLUSIONS
Typical ocular manifestations of Thai patients with BU consisted of bilateral uveitis affecting posterior eye segment with high rate of complications and frequent visual loss.
目的
报告泰国贝赫切特葡萄膜炎（BU）患者的眼部表现和视力结果。
方法
我们回顾了 50 例 BU 患者（31 名男性和 19 名女性）的病历。记录了眼部表现、治疗方式、并发症和视力结果。
结果
76%的患者存在双眼受累，导致 89 只眼受累。全葡萄膜炎和后部葡萄膜炎是最常见的类型。大多数受累眼存在视网膜血管炎，特别是 32/57（56%）眼存在动脉炎。大多数患者接受全身性皮质类固醇和免疫抑制剂（硫唑嘌呤 72%）的联合治疗。在最后一次就诊时，25 只受累眼中有 25 只（28%）视力≤20/200。视力不良的危险因素是就诊时视力较差（p<0.001）和视神经萎缩的发展（p=0.01）。
结论
泰国贝赫切特葡萄膜炎患者的典型眼部表现为双侧后葡萄膜炎，伴有较高的并发症发生率和频繁的视力丧失。
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